B-Type Natriuretic Peptide Can Predict the Medium-Term Risk in Patients With Acute Heart Failure and Preserved Systolic Function

Valle, Roberto; Aspromonte, Nadia; Feola, Mauro; Milli, Massimo; Canali, Cristina; Giovinazzo, P.; Carbonieri, Emanuele; Ceci, Vincenzo; Cerisano, Sergio; Barro, Sabrina; Milani, L.

doi:10.1016/j.cardfail.2005.05.002

Cited by 47 publications

(34 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The fact that BNP is released in patients with isolated diastolic dysfunction may explain why the LV MPI correlated better with BNP concentrations than some of the other echocardiographic measures. 5 The mitral E/Ea is also affected by diastolic filling; however, we found no correlation between it and BNP. The sensitivity, specificity, and predictive powers of the mitral E/Ea were relatively weak for the primary end point.…”

Section: Clinical Correlationcontrasting

confidence: 68%

“…1 Plasma BNP concentrations are elevated in adults with congestive heart failure and can distinguish cardiac from noncardiac causes of dyspnea, correlate with the severity of heart failure symptoms, and predict mortality and hospital readmission. [2][3][4][5][6][7][8][9] Because of this relationship, plasma BNP concentrations have become a useful tool in both the acute care and outpatient settings to facilitate with the diagnosis, triage, and risk stratification of adult patients with congestive heart failure. 10 -13 …”

mentioning

confidence: 99%

See 1 more Smart Citation

B-Type Natriuretic Peptide Predicts Adverse Cardiovascular Events in Pediatric Outpatients With Chronic Left Ventricular Systolic Dysfunction

et al. 2006

View full text Add to dashboard Cite

show abstract

Section: Clinical Correlationcontrasting

confidence: 68%

mentioning

confidence: 99%

B-Type Natriuretic Peptide Predicts Adverse Cardiovascular Events in Pediatric Outpatients With Chronic Left Ventricular Systolic Dysfunction

et al. 2006

View full text Add to dashboard Cite

show abstract

“…[23][24][25][26] Our results are also consistent with previous studies that show an association between elevated BNP levels, poor prognosis, and QOL. [23][24][25][26] Moreover, our results extend other findings demonstrating that increased BNP levels directly correlate with QOL scores such that an increased QOL score is indicative of more functional impairment. 10,16 Additionally, the results of our study show an inverse relationship between BNP and EF as clearly documented by other investigators.…”

Section: Hospitalization and Mortalitysupporting

confidence: 82%

Does Clinician's Knowledge of B‐Type Natriuretic Peptide Levels Translate to Improvement of Quality of Life and Less Hospitalization Days in Patients with Heart Failure?

Ancheta

Evans

Miller

et al. 2009

Progress Cardiovascular Nurs

View full text Add to dashboard Cite

This pilot study was conducted to determine whether clinicians' knowledge of b‐type natriuretic peptide (BNP) levels in individuals with heart failure (HF) correlates with better outcomes including quality of life (QOL) and hospital length of stay (LOS) over a 90‐day period. HF clinic patients were randomized into 2 groups: clinician aware (BNP group; n=50) or blinded to BNP levels (control group; n=42). BNP levels were measured at baseline using the BNP Immunoassay Kit. QOL was measured by the Minnesota Living with Heart Failure (MLWHF) questionnaire, and hospital LOS were measured at baseline and 90 days. There was no significant difference in BNP levels between groups. Compared with baseline scores (46.87 ± 29.63), mean QOL scores at 90 days (37.46 ± 28.67) were not significantly different for both groups. Hospital LOS was also similar for both groups (mean=3 days). BNP levels were significantly correlated with New York Heart Association classification (P=.05), ejection fraction (P=0.0001), creatinine levels (P=0.05), and overall Minnesota Living with Heart Failure Questionnaire scores (P=.01). Clinician's knowledge of BNP levels is not associated with better outcomes of QOL or hospital LOS in HF patients. However, BNP levels are correlated with functional status and physiological parameters. Further research is needed to determine whether other factors influence QOL and hospital LOS of HF patients.

show abstract

“…37,38 If the E/E' value could be used as a surrogate echocardiographic endpoint in patients with HFPSF, the efficacy of medical treatments could be tested and assessed with a smaller numbers of patients and shorter follow-up period. Furthermore, the BNP level has been shown to predict prognosis in patients with HFPSF, 39 so the combination of Doppler indices and BNP may have stronger predictive value in patients with HFPSF.…”

Section: Figmentioning

confidence: 99%

Elevated E/E' Predicts Prognosis in Congestive Heart Failure Patients With Preserved Systolic Function

Okura

Kubo

Asawa

et al. 2009

Circ J

View full text Add to dashboard Cite

Background Although approximately 50% of heart failure patients are reported as heart failure with preserved left ventricular systolic function (HFPSF), echocardiographic prognostic predictors have not been well investigated. Recently, the tissue Doppler-derived index, the ratio of the early transmitral flow velocity and the early mitral annular velocity (E/E'), was reported as useful in predicting prognosis of patients with heart diseases. The purpose of this study was to investigate whether E/E' predicts prognosis in HFPSF. Methods and Results A total of 50 patients with HFPSF (ejection fraction >50%) were consecutively enrolled and studied. Echocardiographic examination was performed on admission and repeated after optimized medical therapy. Cardiac events were defined as death and unplanned hospitalization because of congestive heart failure. Cardiac event-free survival curves from patients with E/E' >15 and E/E' ≤15 at baseline did not differ. On the other hand, patients with E/E' >15 after medical therapy showed significantly lower cardiac event-free survival than patients with E/E' ≤15 (log-rank, P=0.005). By multivariate logistic regression analysis, E/E' >15 after medical therapy was the only independent predictor of cardiac events (P=0.037, risk ratio=6.1, 95% confidence interval: 1.12-33.3) in patients with HFPSF. Conclusions Elevated E/E' after optimized medical therapy may be useful in predicting cardiac events in patients with HFPSF. (Circ J 2009; 73: 86 -91)

show abstract

B-Type Natriuretic Peptide Can Predict the Medium-Term Risk in Patients With Acute Heart Failure and Preserved Systolic Function

Cited by 47 publications

References 34 publications

B-Type Natriuretic Peptide Predicts Adverse Cardiovascular Events in Pediatric Outpatients With Chronic Left Ventricular Systolic Dysfunction

B-Type Natriuretic Peptide Predicts Adverse Cardiovascular Events in Pediatric Outpatients With Chronic Left Ventricular Systolic Dysfunction

Does Clinician's Knowledge of B‐Type Natriuretic Peptide Levels Translate to Improvement of Quality of Life and Less Hospitalization Days in Patients with Heart Failure?

Elevated E/E' Predicts Prognosis in Congestive Heart Failure Patients With Preserved Systolic Function

Contact Info

Product

Resources

About