<b>Pancreatic Duct After Pancreatoduodenectomy:</b> Morphologic and Functional Evaluation with Secretin-Stimulated MR Pancreatography

Monill, J M; Pernas, Juan Carlos; Clavero, Juan A.; Farré, Antonio López; Morales, Antonio; González, Mario Colinabarranco; Artígas, Vicente; Martínez-Noguera, Antonio

doi:10.2214/ajr.183.5.1831267

Cited by 37 publications

(29 citation statements)

References 18 publications

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“…Secretin magnetic resonance cholangiopancreatography (sMRCP) has been used to improve the depiction of the pancreatic ducts, to qualitatively assess pancreatic exocrine function and to assess surgical anastomoses [7][8][9]. Also, sMRCP can be used to assess pancreatic duct integrity in patients post-trauma or post-acute pancreatitis [10] and to quantify pancreatic exocrine output [11].…”

Section: Introductionmentioning

confidence: 99%

Quantitative secretin MRCP (MRCPQ): results in 215 patients with known or suspected pancreatic pathology

Gillams

Lees

2007

Eur Radiol

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Secretin magnetic resonance cholangiopancreatography quantification (MRCPQ) of pancreatic exocrine function correlates well with steatorrhoea and conventional, non-invasive function tests. We report MRCPQ results in a variety of pancreatic conditions. A total of 215 patients [107 male, mean age 46 years (14-78)] were studied. A multi-slice MRCP sequence was performed before and at 2-min intervals after 0.1 ml/kg IV secretin. Change in small intestinal water volume was plotted against time and the flow rate derived from the gradient. Patients were classified using clinical history, MRCP, MR imaging, computed tomography (CT) [150/215 (70%)] and endoscopic retrograde cholangiopancreatography (ERCP) [56/215 (26%)] findings but not MRCPQ results. Mean, standard deviation and 95% confidence intervals were calculated. The one way ANOVA and Student's t-test were used for statistical analysis. Seventy-six patients had chronic pancreatitis, 26 were post-surgical, 34 post-acute pancreatitis, six atrophic pancreatopathy, eight with obstruction, 15 divisum, ten sphincter of Oddi dysfunction, 26 normal and 14 miscellaneous. Significant differences were observed between normals (mean+/-SD; 7.4 +/- 2.9 ml/min) and severe chronic pancreatitis (5.3 +/- 2.4) (P = 0.018), pancreatic atrophy (3.8 +/- 3.1) (P = 0.013) or duct obstruction (5.3 +/- 2.4) (P = 0.047)) and between moderate (7.0 +/- 3.0) (P = 0.03) and severe chronic pancreatitis. MRCPQ can be used to quantify function across the spectrum of pancreatic disease and showed significant differences between several different pathologies.

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Section: Introductionmentioning

confidence: 99%

Quantitative secretin MRCP (MRCPQ): results in 215 patients with known or suspected pancreatic pathology

Gillams

Lees

2007

Eur Radiol

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“…Magnetic resonance cholangiopancreatography with secretin stimulation may be preferred because it is less invasive and provides a functional assessment of the pancreatic duct. 8 In our series, endoscopic retrograde cholangiopancreatography was attempted in 1 patient but failed because the duct could not be cannulated, suggesting a stenosis. The technique of pancreaticogastrostomy outlined in this article is technically easier than revising the existing PJ.…”

Section: Commentmentioning

confidence: 77%

Extended Drainage of the Pancreatic Duct After Pancreaticoduodenectomy

Khithani

Curtis²,

Dickerman³

et al. 2009

Arch Surg

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“…Some clinical studies have reported that pancreatodigestive anastomotic stricture after PD induces impairment of pancreatic exocrine function [13][14][15][16] . Impairment of exocrine function derived from obstructive chronic pancreatitis is thought to be reversible to some degree.…”

Section: Discussionmentioning

confidence: 99%

Repeated Pancreatectomy after Pancreatoduodenectomy

Miura

Takada

Amano

et al. 2007

Journal of Gastrointestinal Surgery

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Pancreatic Duct After Pancreatoduodenectomy: Morphologic and Functional Evaluation with Secretin-Stimulated MR Pancreatography

Abstract: The administration of secretin improves visualization of the pancreatic ducts and helps in the evaluation of remnant pancreatic function after pancreatoduodenectomy.

Cited by 37 publications

References 18 publications

Quantitative secretin MRCP (MRCPQ): results in 215 patients with known or suspected pancreatic pathology

Quantitative secretin MRCP (MRCPQ): results in 215 patients with known or suspected pancreatic pathology

Extended Drainage of the Pancreatic Duct After Pancreaticoduodenectomy

Repeated Pancreatectomy after Pancreatoduodenectomy

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