1981
DOI: 10.1111/j.1365-3083.1981.tb00600.x
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B‐L Antigens (Ia‐like Antigens) of the Chicken Major Histocompatibility Complex

Abstract: This paper reviews the present knowledge of B-L antigens encoded by the chicken B complex as regards to the following aspects: (1) identification and cellular expression, (2) structural studies, (3) evidence for two distinct populations of B-L antigens, (4) mapping of B-L loci of the B complex, (5) B-L and immune response, and (6) the role of the B-L antigens for the control of mixed lymphocyte reactions (MLR) and graft-versus-host (GVH) reactions. It is concluded that B-L antigens of the chicken exhibit exten… Show more

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Cited by 36 publications
(13 citation statements)
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“…vaccine against T cell is more promising and effective. The T cell predicted epitopes is measured by binding affinity between the peptide and MHC alleles but unfortunately there is no database for chicken allele so the human allele is used as model due to similarity between human and chicken alleles (B-F and B-L alleles) [50,51] therefore HLA A, HLA B and HLA C is used for MHC I while HLA DR, HLA DQ and HLA DP is used for MHC II.…”
Section: Discussionmentioning
confidence: 99%
“…vaccine against T cell is more promising and effective. The T cell predicted epitopes is measured by binding affinity between the peptide and MHC alleles but unfortunately there is no database for chicken allele so the human allele is used as model due to similarity between human and chicken alleles (B-F and B-L alleles) [50,51] therefore HLA A, HLA B and HLA C is used for MHC I while HLA DR, HLA DQ and HLA DP is used for MHC II.…”
Section: Discussionmentioning
confidence: 99%
“…They are present on Bcells and on cells of the monocyte/macrophage series but not on unstimulated Tcells and erythrocytes (Ewert and Cooper, 1978). They are composed of two dis tinct noncovalently linked polypeptide chains, a and Û (Crone et al, 1981a). The a chains vary from 30 to 32 kd and the £ chains vaiy from 28 to 29 kd (reduced samples).…”
Section: B-l Antigensmentioning
confidence: 99%
“…B-L phenotyes were assessed using an enzyme linked immunosorbent assay (ELISA) on adherent and immunoglobulin-bearing cells separated from peripheral blood (Loudovaris et al, 1990a). The ELISA typing was confirmed using adherent cells and the indirect immunofluorescence method of Crone et al (1981).…”
Section: Alloantisera and Monoclonal Antibodiesmentioning
confidence: 99%