<b>Effects of a probiotic<i>Lactobacillus acidophilus</i>strain on feed tolerance in dogs with non-specific dietary sensitivity</b>

Pascher, Martina; Hellweg, Petra; Khol-Parisini, A.; Zentek, Jürgen

doi:10.1080/17450390801892583

Cited by 33 publications

(35 citation statements)

References 22 publications

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“…Despite the fact that probiotic products are becoming increasingly used in small animal practice, there are few published studies regarding their clinical effect. Although there are some studies concerning the clinical efficacy of probiotic lactobacilli in chronic enteropathies (Sauter and others 2006, Pascher and others 2008), their effect in acute diarrhoeas has not yet been investigated.…”

Section: Introductionmentioning

confidence: 99%

Effects of a probiotic intervention in acute canine gastroenteritis – a controlled clinical trial

Herstad¹,

Nesheim²,

L’Abée‐Lund³

et al. 2009

J of Small Animal Practice

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OBJECTIVES: To evaluate the effect of a probiotic product in acute self-limiting gastroenteritis in dogs.METHODS: Thirty-six dogs suffering from acute diarrhoea or acute diarrhoea and vomiting were included in the study. The trial was performed as a randomised, double blind and single centre study with stratifi ed parallel group design. The animals were allocated to equal looking probiotic or placebo treatment by block randomisation with a fi xed block size of six. The probiotic cocktail consisted of thermo-stabilised Lactobacillus acidophilus and live strains of Pediococcus acidilactici, Bacillus subtilis, Bacillus licheniformis and Lactobacillus farciminis.RESULTS: The time from initiation of treatment to the last abnormal stools was found to be signifi cantly shorter (P = 0·04) in the probiotic group compared to placebo group, the mean time was 1·3 days and 2·2 days, respectively. The two groups were found nearly equal with regard to time from start of treatment to the last vomiting episode.CLINICAL SIGNIFICANCE: The probiotic tested may reduce the convalescence time in acute self-limiting diarrhoea in dogs.

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Section: Introductionmentioning

confidence: 99%

Effects of a probiotic intervention in acute canine gastroenteritis – a controlled clinical trial

Herstad¹,

Nesheim²,

L’Abée‐Lund³

et al. 2009

J of Small Animal Practice

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“…Digestive tolerance reflects the reaction of the animal to the diet, although different authors may have used different terms such as gastrointestinal tolerance (Knapp et al, 2008) or nonspecific dietary sensitivity (Pascher et al, 2008). Digestive tolerance can be assessed by determining fecal quality (consistency, moisture, volume, odor, and color), and several studies have shown that there is a wide range of digestive tolerance levels among dogs, especially related to body size, breed, or both (Meyer et al, 1999;Weber et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

Influence of dietary protein content and source on fecal quality, electrolyte concentrations, and osmolarity, and digestibility in dogs differing in body size1

Nery

Biourge

Tournier

et al. 2010

Journal of Animal Science

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When fed the same diet, large-breed dogs tend to produce feces of poorer quality compared with small-breed dogs. Moreover, German shepherds, although having a BW similar to Giant Schnauzers, are particularly prone to digestive intolerance, producing feces of poor consistency and increased moisture. Digestive tolerance reflects the reaction of the animal to the diet, and it can be assessed by determining fecal quality (consistency, moisture, volume, odor, and color). This study was conducted to assess the effect of protein source and content on fecal quality, and to determine whether greater digestibility and lesser fecal osmolarity and electrolyte concentrations are associated with improved fecal quality in dogs differing in body size and digestive tolerance. Twenty-seven healthy female dogs were divided into 4 groups according to BW and digestive tolerance: small, medium, large tolerant, and large sensitive. Five diets, varying in protein source (wheat gluten, poultry meal, and a 50:50 mixture of both sources) and concentration (22, 29, and 39% CP on a DM basis for low, medium, and high, respectively) were tested. The present study was divided in 2 phases: 2 diets were studied in a crossover design in phase I, and 3 diets were studied in a Latin square design in phase II. Diets were fed for 14 d, followed by a 12-d transition period. Fecal score (1 = dry and hard feces, to 5 = liquid diarrhea), moisture, electrolytes (Na and K), and osmolarity, and digestibility of DM, energy, fat, CP, and ash were determined. Fecal score and moisture (P < 0.001) were less and overall digestibility (P < 0.001 for DM, CP, fat, ash, and energy) was greater for wheat gluten than for poultry meal diets. Large dogs had the greatest fecal score and moisture (P < 0.001), together with the greatest overall digestibility (P < 0.001 for DM, P = 0.054 for CP, P = 0.005 for ash, and P = 0.003 for energy). Osmolarity was less for wheat gluten-based diets (P < 0.001), and was not affected by dog size. Fecal electrolyte concentration varied mainly with dog group (P = 0.005 for Na, and P < 0.001 for K), being greater in large sensitive dogs compared with small dogs. Wheat gluten was proved to be a suitable protein source for modulating fecal quality in dogs, particularly in sensitive breeds. Poorer fecal quality in large sensitive dogs can be related to greater digestibility and greater fecal electrolyte concentrations, but not to fecal osmolarity.

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“…Probiotics may control enteric colonization by pathogens through different mechanisms, such as interference, reduction or exclusion of bacterial adhesion and also production of substances that inhibit pathogen growth (Reid 1999). In addition, probiotic administration in dogs may have a role in the therapy of other intestinal disorders like inflammatory bowel disease, diarrhea and constipation by different causes or enteric cancer (Pascher et al 2008;Chrzastowska et al 2009) and even may be useful to prevent urogenital infections (Delucchi et al 2008).…”

Section: Introductionmentioning

confidence: 98%

Safety assessment and enteric colonization ability of a native canine Lactobacillus murinus strain

Perelmuter

Fraga

Delucchi

et al. 2010

World J Microbiol Biotechnol

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The aim of this work was to assess the safety and survival in the canine gastrointestinal tract of a native Lactobacillus murinus strain using an in vivo approach. A spontaneous rifampicin-resistant strain generated from a native Lactobacillus murinus strain isolated from dog feces was used in an in vivo administration protocol performed in dogs. The parental strain had been previously characterized in our laboratory, showing interesting probiotic-related properties. The rifampicin-resistant mutant generally exhibited similar properties to the parental strain. When it was administered to healthy dogs, this strain was able to survive in the canine gut and diverse physiological parameters of the animals did not differ from those assessed in non-treated ones. The present in vivo study using a native canine Lactobacillus murinus strain allowed us to conclude that the assessed strain transiently persisted in the canine gut and is safe for administration in dogs. Results of this assay can contribute to the development of new strategies for health promotion in dogs. Future studies will be carried out to evaluate the potential probiotic strain in vivo in dogs under different clinical conditions.

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Effects of a probioticLactobacillus acidophilusstrain on feed tolerance in dogs with non-specific dietary sensitivity

Cited by 33 publications

References 22 publications

Effects of a probiotic intervention in acute canine gastroenteritis – a controlled clinical trial

Effects of a probiotic intervention in acute canine gastroenteritis – a controlled clinical trial

Influence of dietary protein content and source on fecal quality, electrolyte concentrations, and osmolarity, and digestibility in dogs differing in body size1

Safety assessment and enteric colonization ability of a native canine Lactobacillus murinus strain

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