1990
DOI: 10.1002/art.1780330329
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B cells expressing CD5 in minor labial salivary glands of patients with primary Sjögren's syndrome

Abstract: LETTERS 453fects on homologous versus heterologous collagen-induced arthritis in rats.

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Cited by 14 publications
(10 citation statements)
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“…In contrast to ambient flow cytometry data on CD5 in the literature, this may partly explain the paucity of immunohistochemical reports about CD5 in SS/LSG, in spite of the well‐known fact that SS cases may show high levels of circulating CD5 + lymphocytes [32]. Notably, we readily detected a small number of CD5‐stained cells in the SS/LSG, confirming previous isolated immunohistochemical data [33]. The fact that the present SS/LSG CD5 + infiltrates did not overlap with the CD27 + cells indirectly suggests that neither a correlation with T cells (CD45R0) nor with CD20 + B cells can be excluded.…”
Section: Discussionsupporting
confidence: 84%
“…In contrast to ambient flow cytometry data on CD5 in the literature, this may partly explain the paucity of immunohistochemical reports about CD5 in SS/LSG, in spite of the well‐known fact that SS cases may show high levels of circulating CD5 + lymphocytes [32]. Notably, we readily detected a small number of CD5‐stained cells in the SS/LSG, confirming previous isolated immunohistochemical data [33]. The fact that the present SS/LSG CD5 + infiltrates did not overlap with the CD27 + cells indirectly suggests that neither a correlation with T cells (CD45R0) nor with CD20 + B cells can be excluded.…”
Section: Discussionsupporting
confidence: 84%
“…2 did not show any signs of overt autoimmune disease. In patients with Sjogren syndrome, reactive lymphoid lesions are present in the salivary glands, and an infiltration by CD5+ B cells is observed in 5–16% of cases 12. Reactive lymphoid hyperplasia may incubate one or more clones of emerging B cells 13.…”
Section: Discussionmentioning
confidence: 99%
“…In general, the levels of CD5 + B cells are independent of disease activity [50,56,61] in auto-immune conditions. This is consistent with data obtained on repeated blood samples from the same normal volunteers, in whom the percentages of CD5 + B cells were constant over time [62].…”
Section: Other Non Organ-specific Auto-immune Diseusesmentioning
confidence: 99%