B cells and the stressed brain: emerging evidence of neuroimmune interactions in the context of psychosocial stress and major depression
Elizabeth Engler-Chiurazzi
Abstract:The immune system has emerged as a key regulator of central nervous system (CNS) function in health and in disease. Importantly, improved understanding of immune contributions to mood disorders has provided novel opportunities for the treatment of debilitating stress-related mental health conditions such as major depressive disorder (MDD). Yet, the impact to, and involvement of, B lymphocytes in the response to stress is not well-understood, leaving a fundamental gap in our knowledge underlying the immune theo… Show more
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