B-cell specific expression of the murineMyd88L252Pmutation correlates with the establishment of an immunosuppressive microenvironnement in Waldenström macroglobulinemia lymphoplasmacytic lymphoma
Quentin Lemasson,
Ophélie Téteau,
Mina Chabaud
et al.
Abstract:Waldenström macroglobulinemia is a rare and indolent lymphoproliferative disorder genetically characterized by the presence of the L265P mutation in theMYD88gene in nearly each case. Despite its slow progression, Waldenström macroglobulinemia remain incurable due to the lack of specific treatments. The importance of the tumour microenvironment was well documented since the last decade especially concerning the study of solid tumours, but the failures of the immune microenvironment are also experiencing growing… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.