B-cell lymphoma mimicking rhinophyma

Ogden, Stephanie; Coulson, I.H.

doi:10.1111/j.1365-2230.2007.02476.x

Cited by 11 publications

(10 citation statements)

References 8 publications

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“…All colonic biopsy samples showed the predominance of CD4 immunostaining, while a recent report has shown that colonic mucosal lymphocytes are CD8 + predominant in nivolumabinduced colitis. 3 This result suggested that the immunological response is mostly activated by CD4 + T cells in our case.…”

Section: Conflict Of Interestsupporting

confidence: 53%

“…

lymphocytic leukemia) mimicking rosacea or rhinophyma were reported. [2][3][4] Six of the 19 cases had pre-existing rosacea, 2-4 and it has been speculated that neoplastic B cells migrate to the sites of pre-existing rosacea/rhinophyma (Koebner isomorphic phenomenon) or chronic antigenic stimulation by Demodex leads to the development of lymphoma. Although pre-existing rosacea might also contribute to the development of pseudolymphoma in our patient, prior history of rosacea was not apparent.

…”

mentioning

confidence: 99%

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Metaplastic rectal adenocarcinoma into metastatic mucinous carcinoma on the buttock: The efficacy of immunohistochemistry

Kiyohara

Nakamaru

Miyamoto

et al. 2019

The Journal of Dermatology

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Section: Conflict Of Interestsupporting

confidence: 53%

“…

…”

mentioning

confidence: 99%

Metaplastic rectal adenocarcinoma into metastatic mucinous carcinoma on the buttock: The efficacy of immunohistochemistry

Kiyohara

Nakamaru

Miyamoto

et al. 2019

The Journal of Dermatology

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“…Findings of any single reported case were evaluated and the reference lists were checked to identify additional relevant papers. Papers entitled ''Rhinophyma-like [ ]'' and ''[ ] mimicking rhinophyma'' were analyzed before being excluded [34][35][36][37][38][39][40] or included [22] in the current investigation. Finally, papers in which malignancy was erroneously considered as mimicking rhinophyma whereas it developed in a context of diagnosed rhinophyma were included.…”

Section: Methods Of Treatmentmentioning

confidence: 99%

Malignancies Within Rhinophyma: Report of Three New Cases and Review of the Literature

et al. 2011

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These three new cases and the review of 43 cases reported in the literature call attention to the clinical features of carcinomas arising in the context of rhinophyma, raising further concerns about the possible association between these two entities. The need for histologic examination of all surgically removed tissue in patients with rhinophyma is highlighted. Several macroscopic changes, including ulceration, drainage, and a rapid growth pattern, should alarm the physician and should be considered as suspicious of a malignant degeneration. Unexpected clinical modifications of a preexisting long-lasting silent rhinophyma could indicate the possibility of hidden malignancy rather than a rhinophyma itself. Although evidence of an association between the two entities remains inconclusive, half of the malignancies reported in our review were incidental findings associated with rhinophyma. Thus, since rhinophyma should not be considered solely a cosmetic problem, we recommend that all specimens be reviewed by a pathologist and if malignancy is diagnosed, re-excision with clear margins should be achieved when necessary with periodic follow-up.

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“…These tumours can cause severe functional problems, such as difficulty in breathing, as in our patient, or in eating 2 . The diagnosis is mainly based on clinical grounds, although histological study may be necessary to eliminate coexistent occult skin tumours and to distinguish atypical rhinophyma from sarcoidosis, lymphoma, angiosarcoma and sebaceous carcinoma 3–6 …”

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confidence: 88%