Abstract:Xeroderma pigmentosum (XP) is an autosomal recessive disorder caused by
defect in nucleotide excision repair and is associated with increased
incidence of skin cancer. Lymphoblastic leukemia in XP is rare. We
report a case of a 11-year-old boy with XP, who developed B – Acute
lymphoblastic leukaemia (ALL). He was started on Modified BFM
(Berlin-Frankfurt-Münster) ALL Protocol. Tolerance to ALL chemotherapy
was good in our XP patient except for the transient derangement of liver
function tests during induction,… Show more
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