Azithromycin nanoparticles: Cyclic voltammetric study in human blood serum samples at electrochemical analysis

Abdullah, Alaa Laebi; Radhi, Muhammed Mizher; Khelkal, Intesar Nadhum; Naji, Eman Natiq

doi:10.37897/rjn.2020.1.1

Cited by 4 publications

(3 citation statements)

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“…7 and 8, with the Randel equation, the values of diffusion coefficient are calculated below: Df (Ipa1) = 3.06x10 -6 Df (Ipa2) = 5.43x10 -6 Df (Ipc) =1.96x10 -6 The modification of GCE with nanoparticles such as fMWCNT, which has a new phenomenon of the electrochemical conductivity in the cyclic voltammetry by enhancement the redox current that leading to the close diffusion coefficient values as in the above values. These results were indicated that the oxidation-reduction process of the paracetamol compound is a reversible reaction on the modified electrode (fMWCNT/GCE) [18].…”

Section: E Determination Of Diffusion Coefficientmentioning

confidence: 85%

Electrochemical Redox of Acetaminophen Mediated by Functionalize MWCNT Modified Glassy Carbon Electrode

Kareem¹,

Radhi²,

Moosa³

2020

IJEAST

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Glassy carbon electrode (GCE) was modified with functionalize multi wall carbon nanotubes (fMWCNT) by a mechanical attachment technique to produced modified electrode fMWCNT/GCE. The modified working electrode (fMWCNT/GCE) was used to study paracetamol compound (PAR) in KCl solution by cyclic voltammetric technique to find the electrochemical properties of different concentrations, scan rates, pH, diffusion coefficient and reliability. Two oxidation and one reduction current peaks of PAR were found at 750, 375, and 200 mV respectively. PAR compound was examined using the modified electrode to identify the behavior of this compound through oxidation and reduction properties. Good relationships of different concentrations, scan rate, pH of PAR in the electrolyte to prove the sensitive sensor of the modified electrode against to the PAR compound. Diffusion coefficient (Df) values was determined from Randal equation which has closed values of two oxidation and one reduction peaks of Df (Ipa1) = 3.06x10 -6 , Df (Ipa2) = 5.43x10 -6 , and Df (Ipc) =1.96x10 -6 respectively. The search concluded that PAR acts as oxidative drug in alkaline medium and antioxidant in acidic medium.

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Section: E Determination Of Diffusion Coefficientmentioning

confidence: 85%

Electrochemical Redox of Acetaminophen Mediated by Functionalize MWCNT Modified Glassy Carbon Electrode

Kareem¹,

Radhi²,

Moosa³

2020

IJEAST

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“…[4] Many adults and children use it for respiratory tract infections, skin and soft tissue infections, moderate otitis media, sinusitis, pharyngitis, cystic fibrosis, severe bronchitis, GIT infections, tonsil infections, and as an anti- inflammatory in patients with chronic obstructive pulmonary disease [5,6]. And is among the antibiotics with the top sales worldwide [7].There were different published articles for the analysis of AZ in different pharmaceutical and biological forms various analysis techniques are used in these published articles such as spectrophotometry [8][9][10] ,HPLC [11,12], RP-HPLC [13][14][15], glassy carbon [16], cyclic voltammetry [17] flow injection-Amperometric [18] and UV Radiation [19].…”

Section: Introductionmentioning

confidence: 99%

Coated Coated Wire, Coated Graphite and modified carbon paste Electrodes for Potentiometric Determination of Azithromycin

K. Mohammed

2024

Acad. Sci. J.

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For the assessment of the drug azithromycin (AZ) in biological and pharmaceutical samples, three different types of ion selective electrodes were created: the modified carbon paste electrode (MCPE), coated graphite electrode (CGE), and coated wire electrode (CWE). The electrodes followed the Nernst equation in the range (1.0×10 -7 -1.0×10 -1 , 1.0×10 -6 -1.0×10 -1 and 1.0×10 -5 -1.0×10 -1 )M range, with a slope of (58.355, 57.937, and 56,127) mV/decade and a low detection limit of (5.0339×10 -8 , 5.111×10 -7 and 4.8486×10 -6 ) M for (MCPE, CGE and CWE)electrodes respectively. The suggested sensors additionally demonstrated long-term stability and worked following preparation without significant changes in the potential or slope values, the analysis method is very sensitive and selective, and the t-test and F-test at a 95% confidence level were used to perform the statistics precisely and accurately.

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“…This study investigates the effect of drugs on rabbit blood components using cyclic voltammetry [1][2][3][4][5][6]. An adjuvant is a component that enhances the immune response to the vaccine.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Aluminum Nanoparticles on Vaccine-dosed Rabbits Investigated Using Cyclic Voltammetry

Younis¹,

Radhi²,

Al-Mulla³

2023

Nano Biomedicine and Engineering

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This study investigates the effect of aluminum nanoparticles (AL NPs) on vaccines (e.g., poliomyelitis and bacille Calmette-Guérin (BCG) vaccines). Cyclic voltammetry was used to determine the extent of its effect on the blood composition using an in vivo study on blood samples obtained from rabbits injected with poliomyelitic virus and BCG vaccines across a period of four weeks. The oxidation current peaks of the vaccines in the rabbit blood samples were enhanced with increasing doses of AL NPs. AL NPs acted as oxidative reagents to the rabbit blood components.

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Azithromycin nanoparticles: Cyclic voltammetric study in human blood serum samples at electrochemical analysis

Cited by 4 publications

References 0 publications

Electrochemical Redox of Acetaminophen Mediated by Functionalize MWCNT Modified Glassy Carbon Electrode

Electrochemical Redox of Acetaminophen Mediated by Functionalize MWCNT Modified Glassy Carbon Electrode

Coated Coated Wire, Coated Graphite and modified carbon paste Electrodes for Potentiometric Determination of Azithromycin

The Effect of Aluminum Nanoparticles on Vaccine-dosed Rabbits Investigated Using Cyclic Voltammetry

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