2004
DOI: 10.1016/j.accreview.2003.10.066
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Azithromycin for the secondary prevention of coronary heart disease events. The WIZARD study: a randomized controlled trial

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Cited by 119 publications
(155 citation statements)
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“…Trial populations were slightly variable. Six trials were conducted among patients with stable coronary artery disease (10,(13)(14)(15)(16)(17) and six trials involved patients with acute coronary syndromes (18)(19)(20)(21)(22)(23). The remaining trial was conducted among patients scheduled to undergo coronary artery bypass graft surgery (24).…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Trial populations were slightly variable. Six trials were conducted among patients with stable coronary artery disease (10,(13)(14)(15)(16)(17) and six trials involved patients with acute coronary syndromes (18)(19)(20)(21)(22)(23). The remaining trial was conducted among patients scheduled to undergo coronary artery bypass graft surgery (24).…”
Section: Resultsmentioning
confidence: 99%
“…The remaining trial was conducted among patients scheduled to undergo coronary artery bypass graft surgery (24). Three trials (10,13,14) included anti-Chlamydia immunoglobulin (Ig)G titres as part of their inclusion criteria. Trials examined the use of one of four different antibiotics: azithromycin (seven trials) (10,(13)(14)(15)(19)(20)(21), roxithromycin (two trials) (17,22), clarithromycin (three trials) (16,23,24) and gatifloxacin (one trial) (18).…”
Section: Resultsmentioning
confidence: 99%
“…WIZARD (Weekly Intervention with Zithromax for Atherosclerosis and Related Disorder) study 24 failed to find a long term benefit of administering Azithromycin for individuals with stable coronary artery disease, serologic evidence of C. Pneumoniae and past history of myocardial infarction. The ineffectiveness of antibiotics for prevention of secondary cardiovascular events has also been shown in ACES, 25 PROVE IT-TIMI 26 and AZACS 27 trials.…”
Section: Discussionmentioning
confidence: 99%
“…Ис-следование The Northern Manhattan Stroke Study [58,59] показало, что повышенные титры IgA к Chlamydia pneumoniae тесно ассоциируются с высоким риском развития инсульта. Тем не менее попытки примене-ния антибиотиков для профилактики инсульта успешными не были [60].…”
Section: системные и церебральные васкулитыunclassified