Aza‐Claisen Rearrangement

Abstract

This brief review presents an overview on aza-Ciaisen rearrangement with an emphasis on recent developments, e.g. ketene-aza-Ciaisen rearrangement, aza-Ciaisen rearrangement by acid-catalyzed Michael addition and palladium complex-catalyzed aza-Ciaisen rearrangement etc. Contents 1. Introduction 2. Thermal aza-Ciaisen rearrangement 3. Ketene-aza-Ciaisen rearrangement 4. Catalyzed aza-Ciaisen rearrangement 4.1. Bronstead and Lewis acid catalyzed rearrangement 4.2. Aza-Ciaisen rearrangement initiated by acid-catalyzed Michael addition 4.3. Aza-Claisen rearrangement catalyzed by Pd-complexes 5. Conclusion