Ayurvedic clinical profile of COVID-19 – A preliminary report

Manohar, P Ram; Kataria, Sushila; Payyappallimana, Unnikrishnan; Mangalath, Prasad; Nampoothiri, Vasudevan; Sharma, Pooja; Singh, Manish Kumar; Kumar, Kuldeep; Trehan, Naresh

doi:10.1016/j.jaim.2020.05.011

Cited by 31 publications

(21 citation statements)

References 37 publications

(31 reference statements)

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“…At present, the majority of Chinese COVID-19 patients are treated with Traditional Chinese Medicine (TCM) in addition to conventional medicine within the framework of official medical therapy strategies (157)(158)(159). Similar developments are currently evolving in India with Traditional Indian Medicine (TIM) as well (88,90,160).…”

Section: Traditional Medicine Systems (Tms)mentioning

confidence: 99%

The Relevance of Complementary and Integrative Medicine in the COVID-19 Pandemic: A Qualitative Review of the Literature

et al. 2020

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Background: During the COVID-19 pandemic people are facing risks of adverse health effects due to the restrictions implemented such as quarantine measures, reduced social contact, and self-isolation. In this qualitative review, we collected data on potential preventive and therapeutic health benefits of Complementary and Integrative Medicine (CIM) that might be useful during the COVID-19 pandemic. We have reviewed the scientific literature to summarize CIM practices that could be beneficial for improving physical and mental health and well-being of the population under the current pandemic circumstances. It must be noted that this review is not SARS-CoV-2 specific and we explicitly do not intend to make any SARS-CoV-2 specific health claims in this article.Methods and Findings: A qualitative, non-systematic literature review was conducted in Medline to identify literature describing preventive and therapeutic CIM approaches for strengthening mental and physical health. For a variety of CIM approaches clinical evidence was identified, indicating beneficial effects. CIM approaches include specific dietary measures and selected micronutrients, physical activity, techniques from Mind-Body Medicine, single botanicals or botanical compounds, and spending time in nature among others. The effects of CIM measures on conditions like obesity and hypertension are of special relevance here, as these conditions are considered as risk factors for a severe course of COVID-19. Moreover, a possibly direct effect of CIM approaches on immune functions and clinical parameters in respiratory tract infections, such as influenza, were identified. The findings of this review could be helpful for clinicians, patients, and the general population during the current pandemic when discussing and/or considering CIM options.Conclusions: CIM offers a variety of preventive and therapeutic options for strengthening physical and mental resilience, which could also be useful in the current COVID-19 pandemic. The evidence of CIM approaches with a potential benefit in the COVID-19 pandemic in different areas is worth to be analyzed. While this qualitative review has several obvious limitations, it might serve as useful starting point for further research on this topic.

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Section: Traditional Medicine Systems (Tms)mentioning

confidence: 99%

The Relevance of Complementary and Integrative Medicine in the COVID-19 Pandemic: A Qualitative Review of the Literature

et al. 2020

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“…Ayurveda experts have suggested that COVID-19 presents with features comparable to Vatakaphajvara, which can become Sannipatajvara [26][27] [28] with severe presentation, complications and even death in some patients. VK is indicated for the management of Vatakaphajvara and hence has been recommended for management of COVID-19.…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Analysis and Cellular Uptake Study of an Ayurvedic Formulation, Vyaghryadi Kashayam Used in the Clinical Management of COVID-19.

Nandakumar

Mohanan²,

MG³

et al. 2021

Preprint

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Repurposing of drugs is one of the ways to combat COVID-19 and Traditional Chinese Medicine set a precedence for such an approach at the outset of the pandemic. In India, the Ministry of AYUSH has recommended a number of formulations in clinical management of COVID-19. Vyaghryadi Kashayam (VK) is a classical formulation indicated in the management of Vatakaphajvara (a type of fever) which is amongst the medicines recommended for management of COVID-19. The constituents of VK are Zingiber officinale Roscoe, Tinospora cordifolia (Thunb.) Miers and Solanum xanthocarpum Schrad & Wendl. A chemical profile of VK was generated using HPTLC and LC-MS/MS QTOF. Out of the 31 identified phytochemicals in VK, it was found that seven have been reported to have activity against SARS-CoV-2 in prior docking studies. Cellular uptake studies of VK in Caco2 cells showed that all these seven phytochemicals were absorbed by the cells. These findings provide preliminary hints about the potential of VK in clinical management of COVID-19. Further confirmatory in-vitro studies are warranted before large scale clinical studies are initiated.

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“…The sample size was found to be 286 (Ayurvedic clinical profile of COVID-19 -A preliminary study, Puthiyedath R et al May 2020). [17] The study population was chosen through Simple Random Sampling. The subjects who were in the field of health care work in Tamil Nadu within the age group of 18-70 years were included in the study, while the subjects who were not falling under the category of health care work in Tamil Nadu are excluded from study.…”

Section: Methodsmentioning

confidence: 99%

Knowledge and Practice of Possible Ayurvedic, Siddha and Homeopathic Regimens Against Novel Corona Virus Pandemic Among Healthcare Workers: A Cross-Sectional Study

Premnath¹,

Aiswariya²,

Abinaya³

et al. 2021

Int J Ayu Pharm Res

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Background: In the light of the pandemic COVID 19, world’s attention has turned to the immune system and body’s defense force. Identification of the level of epidemic preparedness and understanding of Ayurvedic, Homeopathic and Siddha regimens among health care workers is required to utilize their services in main stream health care effectively. Aim: The aim of this study to access the knowledge and practices of possible Ayurvedic, Homeopathic and Siddha regimens during novel corona virus pandemic. Materials and methods: A cross-sectional survey was undertaken among the health care workers with the help of 15 close ended questions. The one out of six-knowledge question were scored and analysed to identify differences with sociodemographic variables (age and occupation). Response to the three out of five questions on practices were analysed to Identify the differences, differing significantly in both knowledge and practice score. Result: Out of 286 responses, knowledge score significantly differed with age (P-value 0.04) and occupation (P-value 0.01). Practice scores significantly differed with age (P-value 0.01) and occupation (P-value 0.00). Our study shows that 70% of study population is aware of the medicinal properties of Neem, Tulsi and Ashwagandha against COVID 19 and 65% strongly believes the immune boosting effect of Vitamin C and 77% include citrus fruits in their diet. Conclusion: Adopting prophylactic and therapeutic strategies on the basis of Ayurveda, Homeopathy and Siddha are useful to the mankind in fighting against the COVID 19.

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Ayurvedic clinical profile of COVID-19 – A preliminary report

Cited by 31 publications

References 37 publications

The Relevance of Complementary and Integrative Medicine in the COVID-19 Pandemic: A Qualitative Review of the Literature

The Relevance of Complementary and Integrative Medicine in the COVID-19 Pandemic: A Qualitative Review of the Literature

Phytochemical Analysis and Cellular Uptake Study of an Ayurvedic Formulation, Vyaghryadi Kashayam Used in the Clinical Management of COVID-19.

Knowledge and Practice of Possible Ayurvedic, Siddha and Homeopathic Regimens Against Novel Corona Virus Pandemic Among Healthcare Workers: A Cross-Sectional Study

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