Ayurveda & Bioactives as Adjuvant for Dna Modulation in Cancer Treatment & Adverse Drug Reaction [ADR] – A Glimpse of Traditional Indian Nanotechnology

Abstract

Bioactives such as Curcumin and Quercetin and herbs such as “Tulsi”/ Holy basil [_Occimum sanctum_ L.] can provide relief from Adverse drug reaction [ADR] caused by chemotherapy in cancer patients. About 50% patients face moderate ADR issues such as nausea, vomiting, headache, and fewer [20-30%] serious ones [hair loss, loss of fertility and immunity]. The growing recurrence or resistance of cancers to chemotherapy and antimicrobial resistance [AMR] are other emerging challenges in addressing the global cancer burden, among the top causes of death. Two targets of herbal/ bioactive actions include topoisomerase that affects cell replication and telomere length and it may reduce resistance/ recurrence also. Patients with special conditions the old, children and less developed countries with low health budgets can especially develop from it.