Ayurgenomics: A Brief Note on Ayurveda and Their Cross Kingdom Genomics

Abstract

Genomics has led in an era of prognostic, defensive and personalized medicine wherein it is expected that not too far in the future there would be a prototype shift in the practice of medicine from a generalized symptomatic approach to an individualized approach based on his or her genetic makeup. Ayurveda, an ancient Indian system of medicine recognized and experienced in India since 1500 B.C has personalized methodology towards management of health and disease. We thought an addition of Ayurveda and genomics if endeavoured in an efficient way which we call as Ayurgenomics could assistance fill the gap. MicroRNAs (miRNAs) are a class of noncoding small RNAs, which play a vital character in post- transcriptional gene regulation. Currently, numerous study exposed that miRNAs could be transmitted between species to mediate cross-kingdom regulation by assimilating into a specific target gene-mediated governing pathway to apply applicable biological functions. Here, we discuss probable miRNA parallel transfer appliances from one species to another and analyze the relationship between miRNA-mediated cross-kingdom regulation.

Ayurgenomics in Anti-Viral Therapy: A Literature Synthesis

“…In addition, they have comparable roles in modern pharmacological biology. Numerous herbs have been developed for their activities against cancer, dental infections, dermatological diseases, diabetes, and anemia [ 8 ]. Recently, several Ayurvedic antiviral medications have been employed in COVID-19 patients instead of conventional treatment [ 17 ].…”

“…This demonstrates that the mammalian digestive tract can target mammalian genes by absorbing plant miRNAs. Hence, the pandemic can be avoided with the use of stratification of genetic differences, variable immune responses, and clinical aspects of the viruses depending on AG and Prakriti principles [ 8 ].…”

An Ayurgenomics Approach: Prakriti-Based Drug Discovery and Development for Personalized Care

“…The interaction of genetic networks and environmental factors is important for phenotypic diversity in health and disease. Every person has his/her genetic make-up, i.e., Prakriti (Bhadresha et al, 2020). Scientists at CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB) in New Delhi, The ministry of science and technology, hypothesize an opportunity to analyze if the Prakriti-based characterization of individuals has a genetic basis (Prasher et al, 2022).…”