Axillary staging with supine 18F-FDG PET/CT is useful in breast cancer patients undergoing tailored axillary treatment after neoadjuvant systemic therapy according to the MARI protocol

Abstract

Tumor margins were positive in 32/176 IMRs (18%) compared to 50/76 of DRs (66%), respectively ( p < 0.000). There were 56/252 (22%) postoperative complications, consisting mostly of infections requiring antibiotic treatment (64%). The complication rate was higher in patients with DR compared to IMR (36% vs. 16%, p = 0.001). There was no difference, however, in the need for unplanned re-operation (8% vs. 4%).Conclusion: Despite the higher risk of minor complications, DR allows reexcision in case of tumor-positive margins without dismantling the reconstruction. Multidisciplinary pre-operative risk assessment successfully selected cases with an increased risk of positive margins.No conflict of interest. 200Poster Importance of intraoperatory surgical margin assessment for positive margin diagnosis in breast cancer-conserving surgery