Axillary masses as clinical manifestations of male sweat gland carcinoma associated with extramammary Paget’s disease and accessory breast carcinoma: two cases report and literature review

Wu, Jing; Chen, Hongdan; Dong, Juanhui; Cao, Yueqian; Li, Wei; Zhang, Fan

doi:10.1186/s12957-022-02570-w

Cited by 3 publications

(1 citation statement)

References 30 publications

(21 reference statements)

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“…As presented by Wu [ 53 ], male cases of accessory breast cancer and sweat gland cancer associated with extramammary axillary Paget’s disease are uncommon. In clinical diagnosis and treatment, it is necessary to precisely identify the disease and devise an appropriate treatment plan based on the patient’s condition.…”

Section: Resultsmentioning

confidence: 99%

An Update on the General Features of Breast Cancer in Male Patients—A Literature Review

et al. 2022

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Male breast cancers are uncommon, as men account for less than 1 percent of all breast carcinomas. Among the predisposing risk factors for male breast cancer, the following appear to be significant: (a) breast/chest radiation exposure, (b) estrogen use, diseases associated with hyper-estrogenism, such as cirrhosis or Klinefelter syndrome, and (c) family health history. Furthermore, there are clear familial tendencies, with a higher incidence among men who have a large number of female relatives with breast cancer and (d) major inheritance susceptibility. Moreover, in families with BRCA mutations, there is an increased risk of male breast cancer, although the risk appears to be greater with inherited BRCA2 mutations than with inherited BRCA1 mutations. Due to diagnostic delays, male breast cancer is more likely to present at an advanced stage. A core biopsy or a fine needle aspiration must be performed to confirm suspicious findings. Infiltrating ductal cancer is the most prevalent form of male breast cancer, while invasive lobular carcinoma is extremely uncommon. Male breast cancer is almost always positive for hormone receptors. A worse prognosis is associated with a more advanced stage at diagnosis for men with breast cancer. Randomized controlled trials which recruit both female and male patients should be developed in order to gain more consistent data on the optimal clinical approach.

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Section: Resultsmentioning

confidence: 99%

An Update on the General Features of Breast Cancer in Male Patients—A Literature Review

et al. 2022

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Triple negative accessory breast cancer occurring concurrently with primary invasive breast carcinoma：a case report

Chen

Guo

et al. 2023

Preprint

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Introduction Accessory breast cancer (ABC) is a very rare malignancy, and triple negative ABC with ipsilateral invasive in situ breast cancer is extremely infrequent. Binary breast tumors are controversial in terms of surgical methods and comprehensive treatment. Case presentation We share the case of a 64-year-old postmenopausal woman who was found to have an underarm mass for 3 months. Ultrasonography (US) and computed tomography (CT) suggested possible breast cancer with axillary lymph node metastasis. The patient underwent left modified radical mastectomy combined with axillary lymph node dissection. The postoperative pathology suggested a binary tumor, and we performed comprehensive treatment. Conclusion We share the treatment of a rare case of triple-negative para-breast cancer complicated with carcinoma in situ of the breast, hoping to have new therapeutic ideas for the treatment of this disease.

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Triple-negative accessory breast cancer occurring concurrently with primary invasive breast carcinoma: a case report

Chen,

Wu,

Guo

et al. 2024

Front. Surg.

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IntroductionAccessory breast cancer (ABC) is an extremely rare condition, particularly the presence of triple-negative ABC with ipsilateral invasive in situ breast cancer. Binary breast tumors are controversial in terms of surgical methods and comprehensive treatment.Case presentationWe share the case of a 64-year-old postmenopausal woman who presented with an underarm mass for 3 months. Ultrasonography and computed tomography suggested possible breast cancer with axillary lymph node metastasis. The patient underwent a left modified radical mastectomy combined with axillary lymph node dissection. The postoperative pathology confirmed a binary tumor, prompting us to initiate comprehensive treatment.ConclusionWe present the treatment approach for a rare case of triple-negative para-breast cancer complicated with carcinoma in situ of the breast, hoping to contribute new therapeutic ideas for the treatment of this disease.

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Axillary masses as clinical manifestations of male sweat gland carcinoma associated with extramammary Paget’s disease and accessory breast carcinoma: two cases report and literature review

Cited by 3 publications

References 30 publications

An Update on the General Features of Breast Cancer in Male Patients—A Literature Review

An Update on the General Features of Breast Cancer in Male Patients—A Literature Review

Triple negative accessory breast cancer occurring concurrently with primary invasive breast carcinoma：a case report

Triple-negative accessory breast cancer occurring concurrently with primary invasive breast carcinoma: a case report

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