Axillary hyperhidrosis treated with alcoholic solution of aluminium chloride hexahydrate.

Scholes, K T; Crow, K. D.; Ellis, J P; Harman, R.R.M.; Saihan, E.M.

doi:10.1136/bmj.2.6130.84

Cited by 79 publications

(43 citation statements)

References 6 publications

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“…2 Several interventions for hyperhidrosis have been reported. Anticholinergic and antidepressant medications have been found to have side effects, 1 solutions of aluminum chloride or zirconium salts form a temporary plug in the sweat gland, 3 and sympathectomy carries the risk of compensatory sweating. 4,5 Botulinum toxin, which inhibits the release of acetylcholine, has been reported to induce anhidrosis for a median duration of 7 months following its injection into hyperhidrotic palms and axillae; however, a lasting end of the symp- toms has not been observed after numerous treatments.…”

Section: Management Of Postsurgical Hyperhidrosis With Direct Currentmentioning

confidence: 99%

Management of Postsurgical Hyperhidrosis With Direct Current and Tap Water

et al. 2004

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Background and Purpose. Excessive sweating, known as hyperhidrosis, involves the eccrine sweat glands of the axillae, soles, palms, and/or forehead. The use of iontophoresis to reduce or eliminate excessive sweating has been described since 1952. The purpose of this case report is to describe the use of tap water galvanism (TWG) using direct current (DC) with a patient who had postsurgical hyperhidrosis. Case Description. The patient was a 36-year-old male electrician with traumatic phalangeal amputation and postsurgical development of hyperhidrosis. Tap water galvanism was administered using a DC generator, 2 to 3 times per week for 10 treatments. The patient's hands were individually submerged in 2 containers of tap water with the electrodes immersed directly into the containers. Each hand was treated with 30 minutes of TWG at 12 mA. Hyperhidrosis was measured by a 5-second imprint and subsequent tracing of the left hand placed on dry paper toweling. Outcomes. The patient's hyperhidrosis decreased from the full left palmar pad, with a surface area of 10.3ϫ12.0 cm, to a reduced area of wetness that covered a 2.2-ϫ2.7-cm area. The patient returned to work as an electrician without needing absorbent gloves, which had prevented him from performing electrical work. Discussion. Following use of TWG, the patient's palmar hyperhidrosis returned to normhidrosis. [Gillick BT, Kloth LC, Starsky A, Cincinelli-Walker L. Management of postsurgical hyperhidrosis with direct current and tap water. Phys Ther. 2004;84:262-267.]

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Section: Management Of Postsurgical Hyperhidrosis With Direct Currentmentioning

confidence: 99%

Management of Postsurgical Hyperhidrosis With Direct Current and Tap Water

et al. 2004

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“…15 Topical aldehyde agents, such as formaldehyde and glutaraldehyde, have limited use in the treatment of focal hyperhidrosis because they can cause allergic sensitization and localized skin irritation.…”

Section: Topical Treatmentsmentioning

confidence: 99%

Focal hyperhidrosis: diagnosis and management

Haider¹

2005

Canadian Medical Association Journal

222

212

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HYPERHIDROSIS, A CONDITION CHARACTERIZED by excessive sweating, can be generalized or focal. Generalized hyperhidrosis involves the entire body and is usually part of an underlying condition, most often an infectious, endocrine or neurologic disorder. Focal hyperhidrosis is idiopathic, occurring in otherwise healthy people. It affects 1 or more body areas, most often the palms, armpits, soles or face. Almost 3% of the general population, largely people aged between 25 and 64 years, experience hyperhidrosis. The condition carries a substantial psychological and social burden, since it interferes with daily activities. However, patients rarely seek a physician's help because many are unaware that they have a treatable medical disorder. Early detection and management of hyperhidrosis can significantly improve a patient's quality of life. There are various topical, systemic, surgical and nonsurgical treatments available with efficacy rates greater than 90%-95%.

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“…It represents a functional disorder of unknown origin with polygenic inheritance. Whereas relief from axillary hyperhidrosis is achieved by topical application of aluminum chloride hexahydrate in aqueous [1][2][3] or ethanolic [4][5][6] solutions, this therapeutic approach proved little effective in hyperhidrosis of palms or soles [1,2,7]. In addition, surgical excision of axillary skin [8,9] offers a practi cal way of perm anent cure; in palm oplantar hyperhidrosis sympathectomy is the only means of surgical treatment.…”

Section: Introductionmentioning

confidence: 99%

Long-Term Efficacy and Side Effects of Tap Water Iontophoresis of Palmoplantar Hyperhidrosis – the Usefulness of Home Therapy

Hölzle¹,

Alberti²

1987

Dermatology

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Treatment of palmoplantar hyperhidrosis was carried out with a conventional galvanic generator in 40 patients and with a newly developed iontophoresis apparatus, which is suited for home treatment, in 31 patients. The new apparatus is operated by a rechargeable energy source or by batteries and is disconnected from the electrical net during treatment. It conforms to most recent safety regulations as approved by Underwriter’s Laboratory. Hyperhidrosis was completely controlled after 10–12 treatments as revealed by quantitative gravimetric measurements of sweat rates and semiquantitative estimation of starch iodine paper imprints. There was no apparent difference in efficacy between the two apparatuses. Not only hyperhidrosis was abolished, but associated symptoms, such as lividity of palms or soles, acral hypothermia and edema of fingers or toes, also subsided. Skin temperature on palms rose from 29.7 ± 1.8 °C before treatment to 32.2 ± 1.4 °C thereafter. Maintenance treatment was continued on an average for 14 months, in 4 patients for more than 3 years. No loss of efficacy was found during that period. Side effects were minimal and depended upon amperage used. Only slight discomfort during treatment and mild short-lasted skin irritation were observed. Long-term side effects did not occur.

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Axillary hyperhidrosis treated with alcoholic solution of aluminium chloride hexahydrate.

Abstract: often repeatedly, to extremely time consuming tests that they knew could provoke uncomfortable symptoms. Financial help was provided by a research grant from the Oxford RHA(T).

Cited by 79 publications

References 6 publications

Management of Postsurgical Hyperhidrosis With Direct Current and Tap Water

Management of Postsurgical Hyperhidrosis With Direct Current and Tap Water

Focal hyperhidrosis: diagnosis and management

Long-Term Efficacy and Side Effects of Tap Water Iontophoresis of Palmoplantar Hyperhidrosis – the Usefulness of Home Therapy

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