Axial scalable add-on PET/MRI prototype based on four-layer DOI detectors integrated with a RF coil

Nishikido, Fumihiko; Obata, Takayuki; Suga, Mikio; Iwao, Yuma; Tashima, Hideaki; Yoshida, Eiji; Akram, Md. Shahadat Hossain; Yamaya, Taiga

doi:10.1016/j.nima.2022.167239

Cited by 5 publications

(2 citation statements)

References 17 publications

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“…The multiple cells can provide a proportional signal to the input light by summing all the activated cells. Currently, SiPMs have displaced PMTs in most of the modern TOF-PET systems [46][47][48][49][50][51] and combined PET/MR scanners [52][53][54][55][56]. However, there is still space for other MR-compatible photosensors, such as APDs [57,58], being an active research field.…”

Section: Nai (Tlmentioning

confidence: 99%

Recent advances in combined Positron Emission Tomography and Magnetic Resonance Imaging

Galve,

Rodriguez-Vila,

Herraiz

et al. 2024

J. Inst.

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Hybrid imaging modalities combine two or more medical imaging techniques offering exciting new possibilities to image the structure, function and biochemistry of the human body in far greater detail than has previously been possible to improve patient diagnosis. In this context, simultaneous Positron Emission Tomography and Magnetic Resonance (PET/MR) imaging offers great complementary information, but it also poses challenges from the point of view of hardware and software compatibility. The PET signal may interfere with the MR magnetic field and vice-versa, posing several challenges and constrains in the PET instrumentation for PET/MR systems. Additionally, anatomical maps are needed to properly apply attenuation and scatter corrections to the resulting reconstructed PET images, as well motion estimates to minimize the effects of movement throughout the acquisition. In this review, we summarize the instrumentation implemented in modern PET scanners to overcome these limitations, describing the historical development of hybrid PET/MR scanners. We pay special attention to the methods used in PET to achieve attenuation, scatter and motion correction when it is combined with MR, and how both imaging modalities may be combined in PET image reconstruction algorithms.

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Section: Nai (Tlmentioning

confidence: 99%

Recent advances in combined Positron Emission Tomography and Magnetic Resonance Imaging

Galve,

Rodriguez-Vila,

Herraiz

et al. 2024

J. Inst.

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“…The active shimming could only compensate for some of the B 0 drift. The maximum B 0 drift over a FOV of 48 × 48 × 96 mm 3 was ∼700 Hz (5.5 ppm) when the PET insert was powered on and the active shimming was used, which was not ideal, but met the criterion of 10 ppm (Och et al 1992, Nishikido et al 2022.…”

Section: Interferences Of Pet On Mrimentioning

confidence: 99%

Mutual interferences between SIAT aPET insert and a 3 T uMR 790 MRI scanner

Sang¹,

Kuang²,

Wang³

et al. 2023

Phys. Med. Biol.

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Objective: Dual-modality small animal PET/MR imaging provides temporally correlated information on two biochemical processes of a living object. An MRI-compatible small animal PET insert named SIAT aPET was developed by using dual-ended readout depth encoding detectors. In this work, the mutual interferences between SIAT aPET and the 3T uMR 790 MRI scanner of United Imaging was quantitively evaluated. Approach: To minimize the mutual interferences, only the PET detectors and the readout electronics were placed inside the MRI scanner, the major signal processing electronic was placed in the corner of the MRI room and the auxiliary unit was placed in the MRI technical room. A dedicated mouse radio frequency (RF) coil with a transmitter and receiver was developed. The effects of PET scanner on the B0 and B1 field of the MRI scanner and the quality of the MRI images were measured. The effects of MRI imaging on the performance of both the PET detectors and scanner were also measured. Main results: The PET insert affected the homogeneity of the B0 field. The PET insert had no effect on the homogeneity of B1. The mean and standard deviation of the RF noise map were increased by 2.2% and 11.6%, respectively, while the PET insert was placed in the MRI scanner and powered on. Eddy current was produced while the PET insert was placed in the MRI scanner, and it was further increased while the PET insert was powered on. The MR images of a uniform cylindrical water phantom showed that the changes in the SNR and homogeneity were acceptable. The maximum reduction of SNR was less than 11%, and the maximum reduction of homogeneity was less than 2.5%. MRI using common sequences had negligible effects on the flood histograms and energy resolution of the PET detectors, as well as the spatial resolution and sensitivity of the PET scanner. Significance: The mutual interference between the SIAT aPET and the 3T MRI scanner are acceptable. Simultaneous PET/MRI imaging of small animals can be performed with the two scanners.

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Development and performance of SIAT bPET: a high-resolution and high-sensitivity MR-compatible brain PET scanner using dual-ended readout detectors

Kuang,

Sang,

Ren

et al. 2023

Eur J Nucl Med Mol Imaging

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Axial scalable add-on PET/MRI prototype based on four-layer DOI detectors integrated with a RF coil

Cited by 5 publications

References 17 publications

Recent advances in combined Positron Emission Tomography and Magnetic Resonance Imaging

Recent advances in combined Positron Emission Tomography and Magnetic Resonance Imaging

Mutual interferences between SIAT aPET insert and a 3 T uMR 790 MRI scanner

Development and performance of SIAT bPET: a high-resolution and high-sensitivity MR-compatible brain PET scanner using dual-ended readout detectors

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