Awareness of the risk of developing medication-related osteonecrosis of the jaw among bisphosphonate users

El-Ma'aita, Ahmad; Da'as, Noor; Al-Hattab, Mais; Hassona, Yazan; Alrababah, Mohammad A.; Al-Kayed, Mohammad-Awni

doi:10.1177/0300060520955066

Cited by 4 publications

(1 citation statement)

References 29 publications

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“…Of the retrieved publications, dentists in Saudi Arabia presented the lowest level of knowledge: 40.1% considered "Reasonable to good" and only 2.4% considered "Good" 13 . This data is important given recent findings that only 12.4% of Jordan patients using bisphosphonates were aware of the risk of BRONJ due to medication 14 and that only 16.7% Israel patients knew about the need to discontinue the medication before the installation of dental implants 15 . Thus, patients using bisphosphonates are unaware of the drug's peculiarities regarding dental care.…”

Section: Discussionmentioning

confidence: 97%

A survey on brazilian dentists’ awareness, perception, and knowledge of bisphosphonates

Nunes

Anjos²,

Lima³

et al. 2023

Braz.j. of oral sci.

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Aim: The purpose of the study was to analyze the knowledge of dentists in Belo Horizonte, Brazil, about bisphosphonates and their clinical implications. Methods: A cross-sectional questionnaire-based study was conducted with a convenience sample of dentists in Belo Horizonte, in a period of 8 weeks. The questionnaire was self-applied and was structured with 10 items about the dentists’ demographic characteristics, professional profile, and knowledge about bisphosphonates. Associations in the data were analyzed by with the Fischer’s exact test with a significance level of 5%. Results: Of the 214 participating dentists, 163 (76.17%) were women, and 51 (23.83%) were men, with age ranged for 21 to 73 years (mean of 30 years) and mean of 6 years of professional activity. Nearly half (106/49.53%) reported having knowledge about bisphosphonates, and undergraduate courses were the primary source of such information (73/34.11%). Osteoporosis was the most identified indication for use (75/35.04%), although no participants correctly identified all indications. Regarding the drugs’ side effects, only three dentists (1.40%) could correctly identify all responses, with bone necrosis being recognized by the majority (88/41.12%). Sodium alendronate (54/25.23%) and sodium ibandronate (15/7.01%) were the most identified examples of bisphosphonates. Last, only nine dentists (4.20%) could identify all examples of the drugs, and their capacity was associated with self-reported knowledge (p<0.05). Conclusions: More information about bisphosphonates should be disseminated in Belo Horizonte, ideally via better approaches in local undergraduate and postgraduate courses. Until then, knowledge of the basic aspects of bisphosphonates will remain limited.

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Section: Discussionmentioning

confidence: 97%

A survey on brazilian dentists’ awareness, perception, and knowledge of bisphosphonates

Nunes

Anjos²,

Lima³

et al. 2023

Braz.j. of oral sci.

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Osteoporose, Calcium- und Phosphatregulation

Mühlbauer

2023

Arzneiverordnungs-Report 2023

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Awareness and Attitude among Physicians Regarding Bisphosphonaterelated Osteonecrosis of the Jaw (BRONJ): A Cross-sectional Study

Priyadarshini

Ramachandra

Ganganna

2023

CDS

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Background: An invasive dental procedure is considered as one of the risk factors for osteonecrosis of the jaw, especially among patients on bisphosphonates. This study aimed to determine the awareness and perceptions of medical practitioners regarding bisphosphonate-related osteonecrosis of the jaw (BRONJ), and their attitude towards dental referrals of such patients. Methodology: Methodology: This cross-sectional questionnaire-based study was conducted with medical practitioners in and around Mysore city, Karnataka, India, who commonly prescribe bisphosphonates. The sample included orthopaedic doctors, physicians, endocrinologists, and oncologists- divided based on the duration of practice and speciality. Data on the type of practice, awareness of BRONJ, referral to a dentist before/during therapy, and patient education about adverse effects were collected and analyzed. A p value ≤0.05 was considered statistically significant. Results: Among 58 practitioners, 84.5% (49) were aware of the association between bisphosphonates and BRONJ. While 56.9% (33/58) believed dental procedure to be a risk factor, 55.2% (32/58) did not recommend screening of the oral cavity by a dentist before initiation of bisphosphonate therapy. A majority (65.5%) of them educated their patients about adverse effects. Mean knowledge scores varied with specialization (post-graduation vs super specialization= 1.43 vs 2; p = 0.01) but not with the duration of practice (<= 10 years vs >10 years= 1.57 vs 1.4; p= 0.24). Conclusion: The practitioners in our study were oblivious to dental procedures' role in the osteonecrosis of the jaw, highlighting the need of continuing education programs regarding BRONJ for medical and dental professionals. Clinicians who are updated about evidence-based practices and working cooperatively in teams may reduce the incidence of medication-related osteonecrosis of the jaw.

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Awareness of the risk of developing medication-related osteonecrosis of the jaw among bisphosphonate users

Cited by 4 publications

References 29 publications

A survey on brazilian dentists’ awareness, perception, and knowledge of bisphosphonates

A survey on brazilian dentists’ awareness, perception, and knowledge of bisphosphonates

Osteoporose, Calcium- und Phosphatregulation

Awareness and Attitude among Physicians Regarding Bisphosphonaterelated Osteonecrosis of the Jaw (BRONJ): A Cross-sectional Study

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