Awareness of HPV infection and attitudes toward HPV vaccination among Latvian adolescents

Patel, Hersha; Pčolkina, Kristine; Strazdina, Kristine; Viberga, Ilza; Sherman, Susan M.; Tincello, Douglas G.; Redman, C. W. E.; Rezeberga, Dace; Moss, Esther L.

doi:10.1002/ijgo.12117

“…After preliminary observations and review of literature, a set of questionnaires had been developed, the majority of which had been drawn from previous studies [14][15][16] . The questionnaire was translated into Bangla and then translated back to English by a different person to assess validity.…”

Section: Study Toolmentioning

confidence: 99%

Awareness, knowledge about human papillomavirus and attitude towards its vaccine among university students: A Bangladeshi pilot study

Rahman

¹

,

Moonajilin

²

,

Bishwas

³

et al. 2019

Asian J. Health. Sci.

5

0

1

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Objectives: This study aimed to assess the level of awareness and knowledge regarding HPV infection and attitude towards HPV vaccination among the students of Jahangirnagar University (Dhaka, Bangladesh). Methods: A cross-sectional study was conducted in a random sample of 400 students recruited from different disciplines of the University. A self-administered (paper-and-pencil) questionnaire was used to collect data. Results: Among the participants, 177 (44.3%) were males, and 134 (33.5%) were studying in biology disciplines (mean ± SD of age: 21.46 ± 1.93 years). While assessing awareness of HPV, over 60% (257) students reported that they had already heard of HPV (human papillomavirus). In terms of demographic variables, findings revealed that`being female' , being Graduate' , and`being students of biology disciplines' were found to be significant predictors of students' higher level of HPV awareness. Among those aware of HPV, detailed knowledge gaps regarding HPV infection were observed. Only less than half (38.5%) knew that HPV does not show any symptoms and nearly 33% of students were aware that both men and women can get HPV infection. Less than half (47.9%) correctly identified genital skin-to-skin as a mode of transmission. About 42% of students were knowledgeable about the causative relationship between HPV and genital warts, but a few (36.2%) knew that HPV infection may lead to the development of penile cancer. In terms of prevention, only 40.2% knew that the vaccine is a preventive measure of HPV. Only 3.5% (n=14) of the students (females, n=14 and males, n=00) reported to be vaccinated against HPV. Lack of information about the vaccine (53.4%) had been reported as the main reason for not being vaccinated. The modest percentage (59.33%) showed their willingness to get the HPV vaccine. Gender, education level, and marital status were three main factors found influencing students' willingness to receive the vaccine. Conclusion: The results of the study revealed that students were aware of HPV, but detailed knowledge about the infection was poor. Students had a poor understanding of the modes of transmission, health problems associated with HPV and prevention of HPV. Health educational programs can be organized to increase knowledge and awareness about HPV infection.

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“…Interestingly, number of the recipients positive for both, HR-HPV sequences and antibodies, was increasing over the time and number of recipients positive for antibodies only was decreased ( Figure 5). Care Program in 2010, however, uptake of the vaccine is shown to be not sufficient [3].…”

Section: Presence Of Igg Antibodies Against Hr-hpvmentioning

confidence: 99%

“…Prevalence rate of HPV in East Europe is about 21.4% which is much higher in comparison with the global prevalence of 11.7% [1]. Such high prevalence rate could be related with absence of HPV screening program and low vaccination uptake because of poor knowledge on HPV infection among population [2,3].…”

Section: Introductionmentioning

confidence: 95%

Importance of High-Risk Human Papillomavirus Infection Detection in Female Renal Transplant Recipients in the First Year After Transplantation

Cistjakovs¹,

Sultanova²,

Jermakova³

et al. 2018

Preprint

0

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OBJECTIVES: Most of human papilomavirus (HPV) infections are “cleared” by the immune system, however, in cases of immune system suppression infections could lead to development of malignancies. The aim of this study was to find out the frequency of HR-HPV infection in early period after renal transplantation in Latvian recipients receiving immunosuppressive therapy and to follow the progression of the infection up to one year. METHODS: 43 female renal recipients (median age of 48 IQR= 39-58) and 79 practically healthy female individuals (median age of 48 IQR= 42-57) as a control group were enrolled in this investigation. For the detection of HPV infection patients' samples (blood and vaginal swabs) where collected two weeks after transplantation with following collection of six months and one year. Different polymerase chain reactions for HR-HPV genomic sequences detection and commercial ELISA kit for detection of anti-HPV IgG antibodies were used. RESULTS: In this study we show that frequency rate of HR-HPV infection has increased by the one year after transplantation from early stage of immumosuppressive therapy (from 24% to 36%). Also increase of HR-HPV load was detected over the time, showing the highest median viral load at sixth month after transplantation. CONCLUSIONS: From the obtained data follows that it is very important to carefully monitor patients receiving immunosuppression therapy on progression of HR-HPV. In the case of this viral infection presence, immunosuppressive therapy must be attentively adjusted to avoid the HR-HPV infection rapid progression with the subsequent development of CIN or cervical cancer.

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“…Prevalence rate of HPV in East Europe is about 21.4% which is much higher in comparison with the global prevalence of 11.7% [1]. Such high prevalence rate could be related with absence of HPV screening programs and low vaccination uptake because of poor knowledge on HPV infection in the population [2,3].…”

mentioning

confidence: 96%

“…This could be related with several circumstances like low uptake of vaccine in some countries and absence of HPV screening programs, as well as, vaccines do not provide defense from all HPV types. In Latvia HPV vaccination as a routine immunization approach was included in the National Health Care Program in 2010, however, uptake of the vaccine is not sufficient[3,18].The HPV clearance from host's organism requires an adequate immune response, therefore, immunocompromised individuals could be in the risk group of HPV persistent infection development[19]. Because of received immunosuppressive therapy, renal allograft recipients in particular are at high risk of developing persistent infection and HPV associated cancer[20].Recently published cohort study from Denmark shows fivefold increased risk of genital warts (GW) development associated with HPV infection in female kidney transplant recipients in…”

mentioning

confidence: 99%

Importance of High-Risk Human Papillomavirus Infection Detection in Female Renal Transplant Recipients in the First Year after Transplatation

Cistjakovs¹,

Sultanova²,

Jermakova³

et al. 2018

Preprint

View full text Add to dashboard Cite

OBJECTIVES: Most of human papilomavirus (HPV) infections are “cleared” by the immune system, however, in cases of immune system suppression infections could lead to development of malignancies. The aim of this study was to find out the frequency of HR-HPV infection in early period after renal transplantation in Latvian recipients receiving immunosuppressive therapy and to follow the progression of the infection up to one year. METHODS: 43 female renal recipients (median age of 48 IQR= 39-58) and 79 practically healthy female individuals (median age of 48 IQR= 42-57) as a control group were enrolled in this investigation. For the detection of HPV infection patients' samples (blood and vaginal swabs) where collected two weeks after transplantation with following collection of six months and one year. Different polymerase chain reactions for HR-HPV genomic sequences detection and commercial ELISA kit for detection of anti-HPV IgG antibodies were used. RESULTS: In this study we show that frequency rate of HR-HPV infection has increased by the one year after transplantation from early stage of immumosuppressive therapy (from 24% to 36%). Also increase of HR-HPV load was detected over the time, showing the highest median viral load at sixth month after transplantation. CONCLUSIONS: From the obtained data follows that it is very important to carefully monitor patients receiving immunosuppression therapy on progression of HR-HPV. In the case of this viral infection presence, immunosuppressive therapy must be attentively adjusted to avoid the HR-HPV infection rapid progression with the subsequent development of CIN or cervical cancer.

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Awareness of HPV infection and attitudes toward HPV vaccination among Latvian adolescents

Cited by 16 publications

References 22 publications

Awareness, knowledge about human papillomavirus and attitude towards its vaccine among university students: A Bangladeshi pilot study

Awareness, knowledge about human papillomavirus and attitude towards its vaccine among university students: A Bangladeshi pilot study

Importance of High-Risk Human Papillomavirus Infection Detection in Female Renal Transplant Recipients in the First Year After Transplantation

Importance of High-Risk Human Papillomavirus Infection Detection in Female Renal Transplant Recipients in the First Year after Transplatation

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