Awareness of Family and Contact History of Tuberculosis in Generalized Sarcoidosis

Sarcoidosis in tuberculosis-endemic regions: India

“…Reports of previous history of contact with tuberculosis in patients with sarcoidosis [26], similarities in time trends in the prevalence of the two diseases, and ethnic populations with higher incidence of TB having high incidence of sarcoidosis are described in the literature [27,28]. Studies from India reporting patients with TB preceding the development of sarcoidosis or concurrent presence of both diseases have been described [3,4].…”

Sarcoidosis

“…Parsons (1960) in London found that 19% of patients with tuberculosis, 12% of those with sarcoidosis and 2% of controls had a history of recent contact with a known case of tuberculosis. Ten Have and Orie (196 1) in Holland found that 34% of 150 patients with sarcoidosis and a similar proportion, 30%, of those with pulmonary tuberculosis had a history of contact with open tuberculosis.…”

“…history of contact with tuberculosis (Parsons, 1960;Ten Have and Orie, 1961;Bunn and ]ohnston, 1972). Wurm et al (1962) described two sibships in one of which eight cases of sarcoidosis and four of tuberculosis, and in the other four of sarcoidosis three of tuberculosis and two having features of both diseases occured in two generations.…”

Arthritis in sarcoidosis: A multicentric study from India

“…Sarcoidosis and tuberculosis are both marked by granulomatous inflammation in the affected tissues . For reasons that are unclear, sarcoidosis and tuberculosis are often found prevalent in similar patient groups . In areas of the world where tuberculosis is endemic, such as in Southeast Asia, the differentiation of tuberculosis from sarcoidosis presents a significant challenge .…”