Avoidance of allergens and air pollutants in respiratory allergy

Liccardi, Gennaro; Čustović, Adnan; Cazzola, Mario; Russo, María Julieta; D’Amato, Maria; D’Amato, Gennaro

doi:10.1034/j.1398-9995.2001.056008705.x

Cited by 20 publications

(22 citation statements)

References 264 publications

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“…Warner et al[ 26] reported that the use of ionizers could not be recommended in homes of asthmatic subjects to improve their symptoms, but that a significant abatement of airborne allergen concentrations may be useful as part of an allergen avoidance regimen. Ionizers and/or air filtration units did not reduce the levels of mite allergens in indoor environments, since the largest amounts of these allergens remained in settled dust [44]. The development of the most effective way to avoid becoming sensitized and provoking allergic symptoms would be to create the ideal circumstances of getting rid of all allergens from our living environments.…”

Section: Discussionmentioning

confidence: 99%

Decrease in the Allergenicity of Japanese Cedar Pollen Allergen by Treatment with Positive and Negative Cluster Ions

Kawamoto

Oshita

Fukuoka

et al. 2006

Int Arch Allergy Immunol

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Background: Japanese cedar pollinosis is a severe allergic disease in Japan. The most effective means of decreasing allergic inflammation reactions is still avoidance of the aeroallergen. Recently, a novel air purification system using positively and negatively charged cluster ions was developed to create comfortable living environments. We aimed to assess the ability of existing technology to lower allergenicity of Japanese cedar pollen. Methods: A Japanese cedar pollen extract was nebulized from the top of a cylindrical container with 2 or 4 ion-generating devices. The extract in a mist was passed through the space filled with or without plasma cluster ions for 90 s, and the ion-treated or nontreated extract was then collected in a Petri dish at the bottom of the container. Results: The ion-exposed extract was significantly diminished in its reactivities to anti-Cry j 1 or anti-Cry j 2 antiserum and to human allergic sera IgE on ELISA. SDS-PAGE analysis revealed that ion exposure induced protein degradation in the pollen extract. Similarly, the ion treatment impaired about 80% of the binding to pooled sera IgE from patients allergic to Japanese cedar pollen on ELISA inhibition. Furthermore, intracutaneous and conjunctival reaction tests showed a remarkable diminution in the allergenicity of the ion-irradiated extract. Conclusion: Ion irradiation resulted in a remarkable decrease in in vitro and in vivo allergenicities of atomized Japanese cedar pollen extracts.

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Section: Discussionmentioning

confidence: 99%

Decrease in the Allergenicity of Japanese Cedar Pollen Allergen by Treatment with Positive and Negative Cluster Ions

Kawamoto

Oshita

Fukuoka

et al. 2006

Int Arch Allergy Immunol

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“…A number of epidemiological studies show that in the last two decades the prevalence and severity of respiratory allergic diseases such as allergic rhinitis and bronchial asthma seem to be increasing (Antico 2004;Liccardi et al 2001). Nowadays, atopic allergy affects over 25% of the population in the industrialized world (Kurup et al 2002).…”

Section: Introductionmentioning

confidence: 99%

Seasonal and intradiurnal variation of allergenic fungal spores in urban and rural areas of the North of Portugal

et al. 2009

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Because fungal spore emission intensity varies throughout the year and even throughout the day, study of the hourly distribution is an important aspect of aerobiological monitoring. The objective of this work was to determine seasonal and intradiurnal variation of allergenic airborne fungal spores in urban and rural areas. The aerobiological study was performed from 2005 to 2007 using Hirst-type volumetric spore traps. Fungal spore types (Cladosporium, Alternaria, and Aspergillus/Penicillium) were selected according to their allergenic capacity and their frequency in the atmosphere. Cladosporium was the most frequent fungal spore in both locations, together with Alternaria; its concentration was higher during summer whereas Aspergillus/Penicillium was more abundant during autumn. Alternaria and Cladosporium maximum daily spore concentration was reached from 16.00 to 20.00 h. Aspergillus/Penicillium spore distribution differed in the two locations, and although it was difficult to establish a distribution pattern the highest concentration were found during the night. Determination of periods of high concentration may help allergic patients to avoid the daily periods when the allergen concentration is highest.

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“…Аллергены, продуцируемые синантропными чле нистоногими, обладают высокой активностью и ус тойчивостью и способны в течение длительного вре мени персистировать в условиях внутрижилищной среды [4,5]. Характер аллергической реакции зави сит от вида членистоногого, стадии его развития, ис точника аллергенного материала (частицы тела, фе калии, слюна, секрет, другие метаболиты), путей введения аллергена в организм человека, от длитель ности и массивности воздействия аллергена и инди видуальной иммунной реактивности организма че ловека.…”

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“…Кроме того, выявлена прямая корреля ция между плотностью членистоногих и развитием сенсибилизации к ним у больных бронхиальной аст мой (БА) [4,7].…”

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