Avoidance box for mice

Interhemispheric transfer of extinction of the active avoidance reaction in rats.

“…The automated avoidance box was essentially similar to that described by Tenen (1966) for rats and by McKean and Perl (1968) for mice. It consisted of a 53 X 24 cm rectangular box with 51-cmhigh transparent walls, electrifiable grid floor, and Perspex ceiling.…”

[1-[3-(Phenothiazin-10-yl)propyl]-4-piperidinyl]phenylmethanones, a novel class of long-acting neuroleptic agents

“…One of the compounds in the series, l,2 which combines both pharmacophores into a single molecule has proven to be a highly effective neuroleptic agent in clinical trials in man. These results prompted us to prepare and test a short series of phenothiazine derivatives (2)(3)(4)(5)(6) which coupled the benzoylpiperidine pharmacophore with the 10-phenothiazinylpropyl group. I) were prepared by reacting l-(3-chloropropyl)-4-(4-fluorobenzoyl)piperidine (7) with the appropriately substituted phenothiazine (Scheme I).…”