“…Hydrogen-bonds are shown by a dashed line. The in vitro retroviral concerted integration assay has been previously described for ASLV by others (Aiyar et al, 1996;Grandgenett, 2000, 2003;Grandgenett et al, 2009;Hindmarsh et al, 1999Hindmarsh et al, , 2001Vora et al, 2004;Vora and Grandgenett, 2001) and by us (Moreau et al, 2003(Moreau et al, , 2004(Moreau et al, , 2009 as well as for HIV-1, Simian Immunodeficiency Virus (SIV) and PFV. Briefly, the system is composed of a linear donor DNA (D), a plasmid acceptor DNA, and recombinant IN.…”