Avaliação dos impactos do trabalho em turnos noturnos na produção de citocinas inflamatórias salivares e na secreção dos hormônios rítmicos melatonina e cortisol

Reinhardt, Érica Lui

doi:10.11606/t.6.2013.tde-12042013-113122

Cited by 1 publication

(1 citation statement)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For sample size calculation, considering the large interpersonal variability in these biomarkers, the sample size was calculated according to the results of Reinhardt et al (2013) 20 in melatonin levels upon waking between day and night workers, with 5% significance and 80% power, resulting in 36 workers.…”

Section: Methodsmentioning

confidence: 99%

Effect of night-shift work on cortisol circadian rhythm and melatonin levels

Brum¹,

Senger²,

Schnorr³

et al. 2022

Sleep Sci

View full text Add to dashboard Cite

Objectives Night-shift work has been associated with several negative effects on worker’s health, possibly due to circadian desynchronization, sleep deprivation and suppression of nocturnal melatonin secretion including exposure to light during the work shift. The objective of this study was to evaluate the impact of fixed night-shift work versus day-shift work on the sleep-wake cycle and on the night and day levels of cortisol and melatonin. Material and Methods Saliva samples were obtained from 36 individuals, 19 day workers (12 women and 7 men) and 17 night workers (12 women and 5 men) from a university hospital in southern Brazil, with no history of chronic diseases. Demographic and personal information were obtained through a self-administered questionnaire and sleep information by the Munich chronotype questionnaire. Results Salivary cortisol showed normal circadian rhythm in day- and night-shift workers, but was attenuated in night-shift workers during their working hours and on leave days. Night workers sleep fewer hours at night and have higher negative social jet lag than day workers. Conclusion Intervals between night shifts can be beneficial for the recovery of the hypothalamic-pituitary-adrenal axis, minimizing the negative effects on workers’ health, in addition to a preventive approach to aspects related to sleep hygiene and healthy life habits.

show abstract

Section: Methodsmentioning

confidence: 99%