Avaliação do potencial antioxidante e anti-Helicobacter pylori in vitro de extratos de plantas medicinais utilizadas popularmente na região amazônica

Nascimento, Juliana Érica Cirino; Reatgui, Walberson da Silva; Araújo, Luciana Silva de; Ribeiro, Maria Elizelma da Silva; Maia, Daniela Cristina da Silva; Giacomin, Leandro Lacerda; Kitagawa, Rodrigo Rezende; Baratto, Leopoldo Clemente

doi:10.5935/2446-4775.20170023

Cited by 4 publications

(2 citation statements)

References 14 publications

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“…The C. ferrea leaf ethanolic extract demonstrated antioxidant potential, where an ED 50 of 12.45 ± 2.86 µg/mL was obtained, exhibiting a marked activity in radical elimination in the 2,2-diphenyl-1-picrylhydrazil (DPPH) assay using male Sprague–Dawley rats as an experimental model [ 9 ]. Other positive results were also found using the same extract with an EC 50 of 4.4 μg/mL (DPPH) and 2.5 μg/mL 2,2’-azino-bis (3-ethylbenzothiazoline) (ABTS) demonstrating high free radical scavenging activity [ 10 , 73 ].…”

Section: Resultsmentioning

confidence: 98%

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Caesalpinia ferrea C. Mart. (Fabaceae) Phytochemistry, Ethnobotany, and Bioactivities: A Review

et al. 2020

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Caesalpinia ferrea C. Mart., popularly known as “Jucá” or “Pau-ferro”, belongs to the Fabaceae family, and is classified as a native and endemic species in Brazil. Numerous studies that portray its ethnobotany, chemical composition, and biological activities exist in the literature. The present study aimed to systematically review publications addressing the botanical aspects, uses in popular medicine, phytochemical composition, and bioactivities of C. ferrea. The searches focused on publications from 2015 to March 2020 using the Scopus, Periódicos Capes, PubMed, Google Scholar, and ScienceDirect databases. The leaves, fruits, seeds, and bark from C. ferrea are used in popular medicine to treat disorders affecting several systems, including the circulatory, immune, cardiovascular, digestive, respiratory, genitourinary, musculoskeletal, and conjunctive systems. The most commonly found chemical classes in phytochemical studies are flavonoids, polyphenols, terpenoids, tannins, saponins, steroids, and other phenolic compounds. The biological properties of the extracts and isolated compounds of C. ferrea most cited in the literature were antibacterial, antifungal, antioxidant, antiproliferative, anti-inflammatory, and healing potential. However, further studies are still needed to clarify a link between its traditional uses, the active compounds, and the reported pharmacological activities, as well as detailed research to determine the toxicological profile of C. ferrea.

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Section: Resultsmentioning

confidence: 98%

“…C. ferrea leaves, fruits, pods, and bark have been reported in the literature to have antibacterial, antifungal, anti-inflammatory, antioxidant, antidiabetic, and antiulcerogenic properties [ 9 , 10 , 11 , 12 , 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Caesalpinia ferrea C. Mart. (Fabaceae) Phytochemistry, Ethnobotany, and Bioactivities: A Review

et al. 2020

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Phytochemical prospection, evaluation of antibacterial activity and toxicity of extracts of Libidibia ferrea (Mart. ex Tul.) L.P. Queiroz

Macêdo

Santos²,

Pereira³

et al. 2022

Arabian Journal of Chemistry

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Pain Management of Amazon Indigenous Peoples: A Community-Based Study

Moraes

Fabbro

Oliveira

et al. 2021

JPR

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Purpose Indigenous peoples are vulnerable populations that live in remote areas of the Amazon forest with limited access to health-care services. Underreporting and undertreatment of pain is a common event in the general population but little is known about these issues in indigenous peoples. The aim of this study was to investigate the characteristics and cultural aspects of pain management in five ethnicities of the Brazilian Amazon. Materials and Methods Cross-sectional study carried out with adult indigenous individuals from five ethnicities of the Brazilian Amazon over two scientific expeditions (June–July/2017 and February–March/2019). Pain assessment included etiology, intensity, duration, aggravating and alleviating factors, body location, impact of pain on activities of daily living, and treatment. Results Ninety indigenous individuals with a mean age of 41.42 ± 19.59 years (range 19‒98 years) and median age of 37 years participated in the study. Sixty-four individuals (71.1%) reported experiencing pain at the time of interview with intermittent musculoskeletal pain of strong intensity being the more prevalent (back pain: 45.3%, joint pain: 43.7%) followed by headache (26.5%). The main alleviating factors reported were traditional indigenous medicine (21.0%) and rest (30.0%), and physical exertion was the main aggravating factor (69.0%). Most study participants reported that pain affected their mood, activities of daily living, and sleep and that they used both traditional indigenous medicine (78.0%) and conventional medicine (81.0%) for pain relief. Conclusion Musculoskeletal pain is prevalent among indigenous individuals, affects their quality of life, and is partly attributed to their lifestyle. Cultural aspects mediating the pain experience were observed. Traditional indigenous medicine for pain relief remains partially preserved among the ethnic groups investigated. The findings of this study can help improve the delivery care to these vulnerable populations.

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Avaliação do potencial antioxidante e anti-Helicobacter pylori in vitro de extratos de plantas medicinais utilizadas popularmente na região amazônica

Cited by 4 publications

References 14 publications

Caesalpinia ferrea C. Mart. (Fabaceae) Phytochemistry, Ethnobotany, and Bioactivities: A Review

Caesalpinia ferrea C. Mart. (Fabaceae) Phytochemistry, Ethnobotany, and Bioactivities: A Review

Phytochemical prospection, evaluation of antibacterial activity and toxicity of extracts of Libidibia ferrea (Mart. ex Tul.) L.P. Queiroz

Pain Management of Amazon Indigenous Peoples: A Community-Based Study

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