Avaliação da exposição ocupacional ao chumbo em uma metalúrgica um estudo transversal

Menezes-Filho, José A.; Carvalho, Wilson Júnior de Araújo; Spinola, Ademário Galvão

doi:10.1590/s0303-76572003000100007

Cited by 3 publications

(2 citation statements)

References 22 publications

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“…The nonlinear positive correlation observed here has also being demonstrated elsewhere. For example, Menezes‐Filho et al, (2003) evaluated workers in a primary smelting company in Santo Amaro, Bahia, Brazil, and similar behavior was observed. As in our study, an inflection point of ZnPP was observed with PbB levels between 20 and 30 μg/dl.…”

Section: Discussionmentioning

confidence: 73%

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Zinc‐protoporphyrin determination by HPLC with fluorescence detection as a biomarker of lead effect in artisanal pottery workers

Santos

Bandeira

Bah

et al. 2020

Biomedical Chromatography

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Lead (Pb) exposure compromises heme synthesis by inhibiting ferrochelatase, forming zinc‐protoporphyrin (ZnPP). This study aims to validate a method for the determination of ZnPP by HPLC with fluorescence detection and apply this method to evaluate the extent of Pb exposure of artisanal pottery workers. Extraction procedures were tested using both nonacid and acid liquid–liquid extraction. The former presented a better chromatogram and recovery results. The validated method yielded a good resolution of ZnPP and its free form peaks with acceptable precision and accuracy. Total run time was 15 min and ZnPP peak retention time was 5.6 min. We applied this method to evaluate 39 potters (90% male), mean age 40 years (9–80). The medians (ranges) of blood lead, ZnPP and hemoglobin were 16.0 μg/dl (2.2–71.5), 12.6 μg/dl (4.6–279.8) and 15.1 g/dl (11.0–17.8), respectively. Significant differences were observed for blood lead according to gender, age range (>40 years), direct handling of lead oxide and years of occupation. Significantly higher levels of ZnPP were observed in male potters involved with lead glazing activity. The validated method was shown to be simple with one‐step nonacid extraction, good sensitivity, reproducibility and accuracy. Our data shows that these laborers are dangerously exposed to Pb, reflecting the effect on the heme synthesis.

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Section: Discussionmentioning

confidence: 73%

“…It has been shown to habe a significant positive correlation between ZnPP and blood PbB levels above 20–30 μg/dl (Martin et al, 2004). Menezes‐Filho, Carvalho, and Spínola (2003) carried out a study with primary smelter workers in Brazil and observed significant nonlinear positive correlation between PbB and ZnPP levels.…”

Section: Introductionmentioning

confidence: 99%

Zinc‐protoporphyrin determination by HPLC with fluorescence detection as a biomarker of lead effect in artisanal pottery workers

Santos

Bandeira

Bah

et al. 2020

Biomedical Chromatography

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Occupational impacts and adaptation to standards in accordance with Brazilian legislation: The case of Santo Amaro, Brazil

Miranda

Anjos

2018

Safety Science

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Diretrizes para implantação de sistemas de segurança e saúde do trabalho em empresas produtoras de baterias automotivas

Oliveira

Almeida

2010

Gest. Prod.

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O desenvolvimento de Sistemas de Gestão da Segurança e Saúde no Trabalho (SGSST) ganha um significado cada vez mais importante no desempenho das empresas, pois, por meio deles, é possível obter a promoção da saúde e satisfação dos trabalhadores e a redução dos riscos de acidentes. No entanto, para que um SGSST obtenha bons resultados, as empresas precisam estar atentas às dificuldades comumente encontradas durante o seu processo de implantação, procurando solucioná-las de maneira antecipada e estruturada. Pelo exposto, este trabalho tem como principal objetivo apresentar diretrizes, baseadas no referencial teórico e nos resultados dos estudos de caso realizados, para implantação de SGSSTs em empresas fabricantes de baterias automotivas. Para o seu desenvolvimento adotou-se o método de pesquisa qualitativa a partir da realização de dois estudos de caso em empresas fabricantes de baterias automotivas localizadas na cidade de Bauru. Os instrumentos de coleta de dados foram entrevistas semiestruturadas, análise de documentos e observação in loco. Ao final do artigo, são propostas diretrizes relacionadas aos seguintes elementos: alta direção, estratégia organizacional, cultura organizacional, departamento de Segurança e Saúde do Trabalho (SST), técnicos de SST, recursos humanos, treinamento, equipes multidisciplinares, comunicação interna, resistência à mudança, indicadores de desempenho, ferramentas gerenciais para solução de problemas de SST, gestão de projetos, recompensas e incentivos, e integração do sistema.

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Avaliação da exposição ocupacional ao chumbo em uma metalúrgica um estudo transversal

Cited by 3 publications

References 22 publications

Zinc‐protoporphyrin determination by HPLC with fluorescence detection as a biomarker of lead effect in artisanal pottery workers

Zinc‐protoporphyrin determination by HPLC with fluorescence detection as a biomarker of lead effect in artisanal pottery workers

Occupational impacts and adaptation to standards in accordance with Brazilian legislation: The case of Santo Amaro, Brazil

Diretrizes para implantação de sistemas de segurança e saúde do trabalho em empresas produtoras de baterias automotivas

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