Available Instruments to Assess Pain in Infants

Walas, Wojciech; Halaba, Zenon; Latka-Grot, Julita; Piotrowski, Andrzej

doi:10.1542/neo.22-10-e644

Cited by 2 publications

(1 citation statement)

References 94 publications

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“…Nurses play a crucial role in pain assessment, interpreting behavioral, and physiological cues [ 17 – 19 ]. Pain assessment tools, such as the Neonatal Infant Pain Scale (NIPS), validate acute pain in term newborns [ 16 , 20 – 22 ].…”

Section: Introductionmentioning

confidence: 99%

Effect of pacifier and pacifier with dextrose in reducing pain during orogastric tube insertion in newborns: a randomized controlled trial*

Akkaya-Gül,

Özyazıcıoğlu

2024

J Perinatol

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Objective This study aimed to assess the efficacy of pacifier use, with and without 25% dextrose, in reducing pain during orogastric tube insertion in newborns. Study design In a randomized controlled trial involving 60 newborns at a public hospital from April to December 2019, participants were divided into three groups: pacifier (n = 20), pacifier with 25% dextrose (n = 20), and control (n = 20). A pacifier, with and without dextrose, was used for the experimental groups, while the control group performed a routine procedure. Neonatal infant pain scale, crying duration, heart rate (HR), and oxygen saturation (SpO2) were evaluated. Results Results indicated that the control group experienced significantly higher pain levels, elevated HRs, decreased SpO2, and prolonged crying. Conversely, the pacifier with 25% dextrose group showed a notable reduction in crying duration. Conclusion A pacifier, with and without 25% dextrose, effectively reduces pain and improves physiological and behavioral parameters during orogastric tube insertion. Clinical trial number NCT05462964 Clinical trial registration The protocol for this randomized controlled experimental trial is registered on ClinicalTrials.gov. The clinical trial registration number is https://clinicaltrials.gov; NCT05462964.

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Section: Introductionmentioning

confidence: 99%

Effect of pacifier and pacifier with dextrose in reducing pain during orogastric tube insertion in newborns: a randomized controlled trial*

Akkaya-Gül,

Özyazıcıoğlu

2024

J Perinatol

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Assessment of salivary cortisol concentrations for procedural pain monitoring in newborns

Olszewska

Pointinger-Tomasik

Kwinta

2022

Journal of Perinatal Medicine

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Objectives The study aimed to evaluate the usefulness of salivary cortisol (SC) for the assessment of procedural pain intensity in preterm and term newborns. Methods Three groups of neonates (term, 370–416 weeks; moderate to late preterm, 320–366; and very preterm, <320) hospitalized in neonatal intensive care unit were assessed for the study. Response to nappy change, lung ultrasound (LUS), and blood sampling was analyzed. The intensity of pain was evaluated using continuous heart rate and blood oxygen saturation (SpO2) monitoring, Neonatal Infant Pain Scale (NIPS), and SC concentrations. Saliva samples were collected before and 20 min after the procedure’s end. Results Seventy-one infants were examined: 30 term, 21 moderate to late preterm, and 20 very preterm. SC has increased significantly in response to nappy change only in very preterm newborns (2.13 ng/mL [1.55–3.68] vs. 2.84 ng/mL [1.93–9.06], p = 0.01). LUS did not affect concentrations of SC in any group. Significant increase in SC was observed after blood sampling in term and very preterm infants (2.2 ng/mL [1.45–2.92] vs. 4.29 ng/mL [3.88–5.73], p = 0.002, and 1.88 ng/mL [1.47–4.13] vs. 5.3 ng/mL [3.42–8.02], p = 0.002, respectively). A significant correlation between values of SC increase and NIPS scores was found (Spearman’s rank correlation coefficient [rs] = 0.31, p = 0.001). Conclusions We observed the increase in SC concentrations in response to painful stimulus. The presence of a correlation between NIPS scores and SC increase suggests that SC can be used as an objective parameter to assess pain in neonates.

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Available Instruments to Assess Pain in Infants

Cited by 2 publications

References 94 publications

Effect of pacifier and pacifier with dextrose in reducing pain during orogastric tube insertion in newborns: a randomized controlled trial*

Effect of pacifier and pacifier with dextrose in reducing pain during orogastric tube insertion in newborns: a randomized controlled trial*

Assessment of salivary cortisol concentrations for procedural pain monitoring in newborns

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