“…A variety of studies have indicated options to shorten the time from stroke onset to reperfusion, such as cooperative method (9), workflows in hospitals (10,11), rapid diagnoses (12), and public awareness campaigns (13). However, infrastructure and human resources such as spatial accessibility (14)(15)(16), facilities (i.e., the number of beds, equipment), and human resources (17) are critical. Optimization of supply against demand is a crucial issue because the allocation of facilities and human resources affects the onset-to-reperfusion time in stroke.…”