Auxin canalization: From speculative models toward molecular players

Hajný, Jakub; Tan, Shutang; Friml, Jiřı́

doi:10.1016/j.pbi.2022.102174

Cited by 27 publications

(20 citation statements)

References 42 publications

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“…Sachs ( 1975 ) and the review (Hajný et al. 2022 ). These initial observations, together with the discovery of PIN1 and subsequently discovered members of the PIN-FORMED protein family suggested that auxin drives the polarization of its own transporters, and hence the direction of its own transport (reviewed in Merks et al.…”

Section: Introductionmentioning

confidence: 99%

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Scaling relations for auxin waves

et al. 2022

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We analyze an ‘up-the-gradient’ model for the formation of transport channels of the phytohormone auxin, through auxin-mediated polarization of the PIN1 auxin transporter. We show that this model admits a family of travelling wave solutions that is parameterized by the height of the auxin-pulse. We uncover scaling relations for the speed and width of these waves and verify these rigorous results with numerical computations. In addition, we provide explicit expressions for the leading-order wave profiles, which allows the influence of the biological parameters in the problem to be readily identified. Our proofs are based on a generalization of the scaling principle developed by Friesecke and Pego to construct pulse solutions to the classic Fermi–Pasta–Ulam–Tsingou model, which describes a one-dimensional chain of coupled nonlinear springs.

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Section: Introductionmentioning

confidence: 99%

“… 2007 ; Hajný et al. 2022 ). Initial models aimed to explain the formation of transport channels as observed in Sachs’ experiments.…”

Section: Introductionmentioning

confidence: 99%

Scaling relations for auxin waves

et al. 2022

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“…The phytohormone auxin serves as the major endogenous signal behind all this impressive adaptive development 2 . It translates environmental stimuli such as light and gravity into growth responses and aids self-organizing development on account of a feedback regulation between auxin signalling and polar auxin flow 3,4,5 .…”

Section: Introductionmentioning

confidence: 99%

Cell surface auxin signalling directly targets PIN-mediated auxin fluxes for adaptive plant development

Rodríguez

Fiedler

Zou

et al. 2022

Preprint

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The plant hormone auxin and its directional transport across tissues mediate much of the remarkably adaptive and plastic development of higher plants. Positive feedback between auxin signalling and transport is a key prerequisite for self-organizing development including flexible vascular tissue formation and directional growth responses, such as gravitropism. Here we identified a mechanistic link between cell surface ABP1-based auxin perception, the associated TMK1 kinase and PIN auxin transporters. abp1 and tmk1 mutants are defective in auxin-triggered phosphorylation of PIN proteins and in PIN-mediated directional auxin transport. Auxin, via ABP1, induces activation and stabilization of TMK1, thus promoting direct interaction with and phosphorylation of PIN2. Following gravistimulation, the auxin-activated TMK1 acts along the lower root side to reinforce asymmetry in PIN2-mediated auxin fluxes for gravitropic root bending. This ABP1-TMK1-dependent positive feedback on PIN-mediated directional auxin transport is fundamental for robust root gravitropism and presumably also for other self-organizing developmental processes.

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“…In a series of classical experiments, Sachs applied artificial auxin to bean plants, and observed that these become the source new vascular tissue that then joins the existing vasculature; see e.g. [54] and the review [27]. These initial observations, together with the discovery of auxin transporters including PIN1 suggested that auxin drives the polarization of its own transporters, and hence the direction of its own transport (reviewed in [27,44]).…”

mentioning

confidence: 99%

“…[54] and the review [27]. These initial observations, together with the discovery of auxin transporters including PIN1 suggested that auxin drives the polarization of its own transporters, and hence the direction of its own transport (reviewed in [27,44]). Initial models aimed to explain the formation of transport channels as observed in Sachs' experiments.…”

mentioning

confidence: 99%

Scaling Relations for Auxin Waves

Faver¹,

Hupkes²,

Merks³

et al. 2022

Preprint

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We analyze an 'up-the-gradient' model for the formation of transport channels of the phytohormone auxin, through auxin-mediated polarization of the PIN1 auxin transporter. We show that this model admits a family of travelling wave solutions that is parameterized by the height of the auxin-pulse. We uncover scaling relations for the speed and width of these waves and verify these rigorous results with numerical computations. In addition, we provide explicit expressions for the leading-order wave profiles, which allows the influence of the biological parameters in the problem to be readily identified. Our proofs are based on a generalization of the scaling principle developed by Friesecke and Pego to construct pulse solutions to the classic Fermi-Pasta-Ulam-Tsingou model, which describes a one-dimensional chain of coupled nonlinear springs.

show abstract

Auxin canalization: From speculative models toward molecular players

Cited by 27 publications

References 42 publications

Scaling relations for auxin waves

Scaling relations for auxin waves

Cell surface auxin signalling directly targets PIN-mediated auxin fluxes for adaptive plant development

Scaling Relations for Auxin Waves

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