AUXIN BINDING PROTEIN1 Links Cell Wall Remodeling, Auxin Signaling, and Cell Expansion in <i>Arabidopsis</i>

Paque, Sébastien; Mouille, Grégory; Grandont, Laurie; Alabadı́, David; Gaertner, Cyril; Goyallon, Arnaud; Muller, Philippe; Primard-Brisset, Catherine; Sormani, Rodnay; Blázquez, Miguel Á.; Perrot‐Rechenmann, Catherine

doi:10.1105/tpc.113.120048

Cited by 77 publications

(74 citation statements)

References 79 publications

(144 reference statements)

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“…These findings cannot be reconciled easily with the embryo lethal phenotypes of the two original lethal T-DNA insertion lines (Chen et al, 2001;Tzafrir et al, 2004;Meinke et al, 2008;Sassi et al, 2014), the phenotypes of the ABP1 antisense line (Braun et al, 2008;Chen et al, 2014), the phenotypes of the lines expressing anti-ABP1 monoclonal antibody fragments (Braun et al, 2008;Tromas et al, 2009;Paque et al, 2014), or the phenotypes of the abp1-5 TILLING allele (Robert et al, 2010;Xu et al, 2010;Effendi et al, 2013;Chen et al, 2014) and thus require explanation. The situation is far from clear at present and might be explained, for example, by off-target effects in the antibody and antisense expression lines in conjunction with background mutations in the knockout lines as well as in the abp1-5 allele.…”

Section: Introductionmentioning

confidence: 92%

“…Conversely, examined abp1-5 SNPs on Chromosomes 1, 2, 4, and 5 do not appear to be present in either the Ws-2 or Landsberg erecta (Ler-0) ecotypes ( Figure 4B). The abp1-5 lines characterized in other publications (Robert et al, 2010;Baster et al, 2013;Effendi et al, 2013;Chen et al, 2014;Paque et al, 2014;Xu et al, 2014) likely carry a distinct subset of background mutations, depending on mutation segregation as a result of crosses made to create abp1-5 carrying molecular reporters. The extent to which these abp1-5 background mutations contribute to abp1-5 phenotypes is unknown; in addition, these mutations are likely to have segregated independently and variably as labs have made additional crosses with abp1-5, increasing the complexity of understanding abp1-5 phenotypes for which no complementation line was used.…”

Section: Abp1-5 Contains Numerous Background Mutationsmentioning

confidence: 99%

“…Reported morphological changes in these lines include small epinastic cotyledons and leaves caused by decreased cell size and infrequent cell divisions (Braun et al, 2008), reduced root growth (Tromas et al, 2009), decreased epidermal pavement cell lobing (Xu et al, 2010), reduced hypocotyl elongation in dark-grown seedlings (Paque et al, 2014), and long hypocotyls when grown under low red:far-red light conditions (Effendi et al, 2013). On a molecular level, affecting ABP1 function using antisense, antibodies, or the abp1-5 allele has been reported to result in decreased auxin transcriptional responses (Tromas et al, 2009), reduced activation of ROP small GTPases (Xu et al, 2010), enhanced auxin efflux protein internalization in epidermal pavement cells (Xu et al, 2010), reduced Brefeldin A-induced internalization of auxin efflux proteins in root cells (Robert et al, 2010;Chen et al, 2012), altered auxin-responsive rearrangement of microtubules (Chen et al, 2014), and altered xyloglucan structure (Paque et al, 2014). These phenotypes suggest roles for ABP1 in many processes.…”

Section: Introductionmentioning

confidence: 99%

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Genome Sequencing of Arabidopsis abp1-5 Reveals Second-Site Mutations That May Affect Phenotypes

Enders

Yang

et al. 2015

The Plant Cell

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Auxin regulates numerous aspects of plant growth and development. For many years, investigating roles for AUXIN BINDING PROTEIN1 (ABP1) in auxin response was impeded by the reported embryo lethality of mutants defective in ABP1. However, identification of a viable Arabidopsis thaliana TILLING mutant defective in the ABP1 auxin binding pocket (abp1-5) allowed inroads into understanding ABP1 function. During our own studies with abp1-5, we observed growth phenotypes segregating independently of the ABP1 lesion, leading us to sequence the genome of the abp1-5 line described previously. We found that the abp1-5 line we sequenced contains over 8000 single nucleotide polymorphisms in addition to the ABP1 mutation and that at least some of these mutations may originate from the Arabidopsis Wassilewskija accession. Furthermore, a phyB null allele in the abp1-5 background is likely causative for the long hypocotyl phenotype previously attributed to disrupted ABP1 function. Our findings complicate the interpretation of abp1-5 phenotypes for which no complementation test was conducted. Our findings on abp1-5 also provide a cautionary tale illustrating the need to use multiple alleles or complementation lines when attributing roles to a gene product. INTRODUCTIONThe plant hormone auxin regulates cell division and cell expansion to affect all aspects of plant growth (reviewed in PerrotRechenmann, 2010). Auxin regulates a wide range of developmental processes, and tight control of auxin response is maintained by multiple modes of regulation. These include regulating auxin biosynthesis and metabolism, transport, and signaling (reviewed in Enders and Strader, 2015). To date, nuclear auxin signaling components have been well characterized (reviewed in Chapman and Estelle, 2009;Salehin et al., 2015). In addition, a nontranscriptional auxin response pathway has been proposed, with AUXIN BINDING PROTEIN1 (ABP1) acting in the apoplast as an auxin receptor and transmitting a cytoplasmic signal to regulate auxin responses such as auxin transport and cytoskeletal rearrangements (reviewed in Shi and Yang, 2011;Sauer et al., 2013).Study of ABP1 has a long, complicated history. Experiments demonstrating auxin binding activity for ABP1 were published as early as the 1980s (reviewed in Jones, 1994). Reverse genetics proved to be a complicated approach to study ABP1 function in Arabidopsis thaliana, as two independently generated abp1 mutants, presumed to be null alleles, appeared to be embryo lethal (Chen et al., 2001;Tzafrir et al., 2004;Meinke et al., 2008;Sassi et al., 2014). Knockdown lines of ABP1 provided some ability to study ABP1 function by reverse genetics. Arabidopsis lines expressing an inducible ABP1 antisense transcript or an inducible single-chain fragment variable scFv12 (David et al., 2007) from a monoclonal antibody raised to ABP1 (Leblanc et al., 1999), targeted to either the apoplast (SS12S) or the endoplasmic reticulum (SS12K), led to phenotypes consistent with decreased auxin activity (Braun et al., 2008;Tromas et al.,...

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Section: Introductionmentioning

confidence: 92%

Section: Abp1-5 Contains Numerous Background Mutationsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Genome Sequencing of Arabidopsis abp1-5 Reveals Second-Site Mutations That May Affect Phenotypes

Enders

Yang

et al. 2015

The Plant Cell

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“…It is involved in a broad range of cellular responses to auxin including cell division and expansion and auxinregulated gene expression (Tromas et al, 2010;Sauer and Kleine-Vehn, 2011;Shi and Yang, 2011). ABP1 has long been proposed as a candidate auxin receptor to mediate auxin action in plant and to control growth and development throughout plant life (Paque et al, 2014). The developmental switch from a differentiated cell state to a dedifferentiated, dividing, and embryogenic state involves the general reorganization of chromatin and the overall reprogramming of gene expression (Dudits et al, 1995).…”

Section: Introductionmentioning

confidence: 99%

Molecular investigations of the somatic embryogenesis recalcitrancein the cherry (Prunus cerasus L.) rootstock CAB 6P

Mahmoud¹,

Jedidi²,

Delporte³

et al. 2017

Turk J Biol

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IntroductionSomatic embryogenesis is the process by which somatic cells, under induction conditions, generate embryogenic cells that go through a series of morphological and biochemical changes that result in the formation of somatic embryos (Quiroz-Figueroa et al., 2006). This process is feasible because plants possess cellular totipotency, by which individual somatic cells can regenerate a whole plant (Vasil and Vasil, 1972). The acquisition of embryogenic competence by somatic cells is a complex process that comprises several phases: dedifferentiation, cell reactivation, cell divisions, and various metabolic and developmental reprogramming steps (Ochatt, 2010). The technique of embryogenesis makes an attractive tool not only for mass production but also for crop improvement and genetic transformation (Pérez-Clemente et al., 2004;Quiroz-Figueroa et al., 2006;Namasivayam, 2007). However, the initiation of somatic embryogenesis in plants depends on both extrinsic and intrinsic factors.Among the various extrinsic factors that may induce an embryogenic pathway of development, plant growth regulators, especially auxins, have been known to be implicated in cell cycle regulation, cell division, and differentiation (Del Pozo and Manzano, 2014) as well as in the induction of somatic embryogenesis (Pasternak, 2002). Picloram (4-amino-3,5,6-trichloropicolonic acid), a synthetic auxin, is particularly effective for induction of cell division, proliferation, and further regeneration such as somatic embryogenesis in a range of plant species (Barro et al., 1999;Sanchez-Romero, 2005;Gomes et al., 2006). It acts by inducing auxin sensitivity in nondividing cells that are arrested in G1 (growth phase), enabling them to reenter the S phase (DNA replication) and mitosis (He et al., 2010).Regarding intrinsic factors, genotype is the most determinant in embryogenic competence (Fehér, 2008;Ochatt et al., 2010;Isah, 2016). Various groups, families, and genera are still regarded as recalcitrant to embryogenesis, like Prunus (Druart, 1999). Such recalcitrance has handicapped and delayed the exploitation of biotechnology approaches for breeding in many species and was and still is the subject of research in many laboratories (Ochatt et al., 2010).

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“…Auxin widely regulates plant development, such as by coordinating the placement and patterning of organs and cells, most of this research were based on the model plant, Arabidopsis, for its small and completely sequenced genome [1,2,3,4,5,6,7]. In Nicotiana, auxin aslo regulate cell division, polarity formation, seed germination as well as stomata movement [8,9,10].…”

Section: Introductionmentioning

confidence: 99%

Difference of auxin transport inhibitor treatment on several development processes between Arabidopsis and Nicotiana seedlings

Zhou¹,

Chen²,

Chen³

et al. 2016

Proceedings of the 2016 International Conference on Civil, Structure and Environmental Engineering

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Abstract. Auxin transport and signaling enforce stomatal patterning as well as the size of their stem cell compartment in Arabidopsis. But it remains unknown whether this regulation is also existed in other species. We use Nicotiana as an example to analysis the function of auxin transport inhibitor NAP and BFA on its stomatal developement on the epidermis of cotyledon taking Arabidopsis as control. Here we report that there is an inter-specific difference between Nicotiana and Arabidopsis under exogerous auxin inhibitors (NPA and BFA) treatment in stomatal development. No stomatal development defect can be detected in Nicotiana treated with NPA and BFA under the same concentration which can induce patterning and morphogenesis abnormality of stoma in Arabidopsis.

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AUXIN BINDING PROTEIN1 Links Cell Wall Remodeling, Auxin Signaling, and Cell Expansion in Arabidopsis

Cited by 77 publications

References 79 publications

Genome Sequencing of Arabidopsis abp1-5 Reveals Second-Site Mutations That May Affect Phenotypes

Genome Sequencing of Arabidopsis abp1-5 Reveals Second-Site Mutations That May Affect Phenotypes

Molecular investigations of the somatic embryogenesis recalcitrancein the cherry (Prunus cerasus L.) rootstock CAB 6P

Difference of auxin transport inhibitor treatment on several development processes between Arabidopsis and Nicotiana seedlings

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