Auxiliary cables for generating stations

Smith, Frank; Norell, E. G.

doi:10.1109/ee.1952.6437785

Cited by 2 publications

(2 citation statements)

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“…Results from the present experiments are in good agreement with those from the intracerebral injection of labeled fatty acid precursors (13,15). Differences in turnover of brain phosphoglycerides at a subcellular level have been reported also by injecting 14C-acetate intraperitoneally into developing rats (18). In a previous study, Mead and Dhopeshwarkar (19) examined the metabolism of fatty acids in brain by feeding the rats labeled fatty acids.…”

Section: Microsomessupporting

confidence: 86%

Essential fatty acid deficiency: Metabolism of 20∶3(n−9) and 22∶3(n−9) of major phosphoglycerides in subcellular fractions of developing and mature mouse brain

Sun

Winniczek

et al. 1975

Lipids

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Essential fatty acid deficiency was initiated in young and mature mice. The metabolism of 20:3(n-9) and 22:3(n-9) in brain subcellular fractions was followed after the mice were switched from the deficient diet to a corn oil supplemented diet. After switching to the supplemented diet, the proportions of (n-9) polyunsaturated fatty acids in brain in both groups of mice decreased with time. The rate of disappearance of (n-9) polyunsaturated fatty acids was faster in the young groups than in the mature group. In the developing mice, the half-linves of the (n-9) polyunsaturated fatty acids in the total ethanolamine phosphoglycerides of brain microsomal, synaptosomal, and myelin fractions were 3, 10, and 15 days respectively. In the mature group, the half-lives for 20:3(n-9) in diacyl-glycerophosphorylethanolamine of microsome, synaptosome, and myelin fractions were 8-10, 10, and 22 days, respectively; and the half-lives for 22:3(n-9) in alkenylacyl-glycerophosphorylethanolamine of the same subcellular fractions were 8-12, 28, and rate of disappearance of 20:3(n-9) in brain was faster in the diacyl-glycerophosphorylethanolamine than in the alkenylacyl-glycerophosphorylethanolamine. These results demonstrate that the metabolism of (n-9) polyunsaturated fatty acid in brain phosphoglycerides during recovery from essential fatty acid deficiency not only varies with age, but also depends upon individual phosphoglycerides present in each subcellular fraction.

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Section: Microsomessupporting

confidence: 86%

Essential fatty acid deficiency: Metabolism of 20∶3(n−9) and 22∶3(n−9) of major phosphoglycerides in subcellular fractions of developing and mature mouse brain

Sun

Winniczek

et al. 1975

Lipids

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“…The lipids of the mitochondrial fraction were predominantly from mitochondria but may also include a small amount of lipid from the plasma membranes of the nerve ending particles. Values for the lipid composition of brain mitochondrial fractions are available for the ox (19), guinea pig (20), and rat (21)(22)(23)(24)(25)(26). There is general agreement on a protein-lipid weight ratio of 2:1 and cholesterol-lipid phosphorus molar ratio of 1:3.…”

Section: Discussionmentioning

confidence: 95%

The acyl and Alk‐1‐enyl groups of the major phosphoglycerides from ox brain myelin and mouse brain microsomal, mitochondrial and myelin fractions

Sun

Horrocks

1970

Lipids

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The major phosphoglycerides from ox brain myelin and mouse brain microsomal, mitochondrial and myelin fractions were separated by preparative thin layer chromatography. Alk-l-enyl groups from the alk-1 -enyl acyl gly c er o p hosphorylethanolamines were reacted with 1,3-propanediol to form the 1,3-dioxolane derivatives. Acyl groups were converted to the methyl ester derivatives and the acyl groups from alk-1enyl acyl glycerophosphorylethanolamines and diacyl glycerophosphorylethanolamines were also determined separately. The acyl and alk-l-enyl group compositions of the phosphoglycerides from microsomal and mitochondrial fractions were quite similar. The ethanolamine and serine phosphoglycerides contained large amounts of 18:0, 18:1, 20:4 and 22:6 acyl groups. The choline phosphoglycerides had small amounts of polyunsaturated acyl groups and large amounts of 16:0, 18:1 and 18:0 acyl groups. The mitochondrial cardiolipins contained unusual amounts of several acyl groups including 18: 1, 52%; 18:2, 6%; and 16.1, 4%. A large portion of the mouse brain 18:2 is in that fraction. The myelin phosphoglycerides were deficient in saturated and 22:6 groups and markedly enriched in 18:1 and 20" 1 groups when compared with the corresponding microsomal or mitochondrial phosphoglycerides.

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Auxiliary cables for generating stations

Cited by 2 publications

References 0 publications

Essential fatty acid deficiency: Metabolism of 20∶3(n−9) and 22∶3(n−9) of major phosphoglycerides in subcellular fractions of developing and mature mouse brain

Essential fatty acid deficiency: Metabolism of 20∶3(n−9) and 22∶3(n−9) of major phosphoglycerides in subcellular fractions of developing and mature mouse brain

The acyl and Alk‐1‐enyl groups of the major phosphoglycerides from ox brain myelin and mouse brain microsomal, mitochondrial and myelin fractions

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