Autotransfusion in Major Orthopedic Surgery: Postoperative Evaluation

Borghi, Battista; Pignotti, Elettra; Famelli, G.; Baroncini, S

doi:10.1177/039139889802106s18

Cited by 3 publications

(3 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study the number of thromboembolic complications was smaller than the percentage reported by other studies (10). Interestingly, in our study, deep venous thrombosis and pulmonary embolism were lower in those patients who had Hb levels less than 8 g/dl.…”

Section: Discussioncontrasting

confidence: 77%

“…Haemodilution, when it is not contraindicated and well tolerated by the patients also reduces the risk of thromboembolism (10)(11)(12).…”

Section: Discussionmentioning

confidence: 99%

“…Several studies on severe haemodilution have shown that correct organ perfusion and tissue oxygenation are guaranteed in the presence of normovolemia (8, 9). Intentional haemodilution is also of clinical efficacy in reducing thromboembolic risks (10)(11)(12) in consideration of hypercoagulable state (13) and in causing a peak of endogenous erythropoietin (EPO) levels (14).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Effects of Predeposit and Intentional Perioperative Haemodilution on Blood Saving Program in Major Orthopaedic Surgery

et al. 1999

Self Cite

View full text Add to dashboard Cite

In this study we evaluated the effects of predeposit and intentional perioperative haemodilution on a blood saving program in major orthopaedic surgery. We demonstrated that autologous blood phlebotomy and maintenance of optimal levels of perioperative haemodilution by delaying blood transfusion, even autologous, are efficient techniques in reducing homologous, red blood cell (HRBC) transfusion. Patients who received autologous red blood cell (ARBC) or HRBC more than one day after surgery, while having Hb values <8 g/dl, are less at risk of needing the first or additional HRBCs. In conclusion, predeposit and intentional haemodilution obtained by delaying blood transfusions, even autotransfusional, is a correct way of conducting a blood saving program (BSP) in major orthopaedic surgery. These techniques are clinically effective in avoiding or reducing HRBC transfusion.

show abstract

Section: Discussioncontrasting

confidence: 77%

“…Haemodilution, when it is not contraindicated and well tolerated by the patients also reduces the risk of thromboembolism (10)(11)(12).…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of Predeposit and Intentional Perioperative Haemodilution on Blood Saving Program in Major Orthopaedic Surgery

et al. 1999

Self Cite

View full text Add to dashboard Cite

show abstract

Granulocyte transfusion in leukopenic children by simplified leukapheresis of related donors

et al. 1998

View full text Add to dashboard Cite

In this prospective, randomised, double-blind study, we investigated the effect of epidural anaesthesia and an antifibrinolytic agent, Aprotinin (500,000 KIU in bolus before surgery and 500,000 KIU h-1 in drip form during surgery), on intra and postoperative blood loss and transfusion requirements in total hip arthroplasty. Sixty patients were allocated randomly to four groups (A: epidural + general anesthesia + Aprotinin, B: epidural + general anesthesia + placebo (equal volume), C: general anaesthesia + Aprotinin, D: general anaesthesia + placebo). Postoperative analgesia: epidural analgesia in groups A and B, systemic analgesia with opiates in groups C and D. Blood loss during surgery was monitored and salvaged with the Compact-A Dideco, and postoperative blood loss with the BT 797 Recovery Dideco for the first 24 hours. Perioperative blood loss, frequency and quantity of transfusions were significantly higher in group D (p < 0.0001). Total blood loss was reduced by 31.3% by epidural anaesthesia, 20.4% by Aprotinin and 51.4% using a combination of the two techiniques.

show abstract

Reducing perioperative blood loss in patients undergoing total hip arthroplasty

et al. 1999

View full text Add to dashboard Cite

In this prospective, randomised, double-blind study, we investigated the effect of epidural anaesthesia and an antifibrinolytic agent, Aprotinin (500,000 KIU in bolus before surgery and 500,000 KIU h(-1) in drip form during surgery), on intra and postoperative blood loss and transfusion requirements in total hip arthroplasty. Sixty patients were allocated randomly to four groups (A: epidural + general anesthesia + Aprotinin, B: epidural + general anesthesia + placebo (equal volume), C: general anaesthesia + Aprotinin, D: general anaesthesia + placebo). Postoperative analgesia: epidural analgesia in groups A and B, systemic analgesia with opiates in groups C and D. Blood loss during surgery was monitored and salvaged with the Compact-A Dideco, and postoperative blood loss with the BT 797 Recovery Dideco for the first 24 hours. Perioperative blood loss, frequency and quantity of transfusions were significantly higher in group D (p<0.0001). Total blood loss was reduced by 31.3% by epidural anaesthesia, 20.4% by Aprotinin and 51.4% using a combination of the two techniques.

show abstract

Autotransfusion in Major Orthopedic Surgery: Postoperative Evaluation

Cited by 3 publications

References 9 publications

Effects of Predeposit and Intentional Perioperative Haemodilution on Blood Saving Program in Major Orthopaedic Surgery

Effects of Predeposit and Intentional Perioperative Haemodilution on Blood Saving Program in Major Orthopaedic Surgery

Granulocyte transfusion in leukopenic children by simplified leukapheresis of related donors

Reducing perioperative blood loss in patients undergoing total hip arthroplasty

Contact Info

Product

Resources

About