Autosomal dominant hypodontia with nail dysgenesis

New form of hidrotic ectodermal dysplasia in a Lebanese family

“…However, dysplastic nails may be apparent only in childhood [Hudson and Witkop, 1975], and the patients reported by Fried [1977] may have developed this anomaly at a later age. Moreover, in Fried's patient, the hair had a diameter that was much narrower than the average, as did the sibs in the present report.…”

Witkop tooth and nail syndrome: report of two cases in a family

“…Taurodontia is not a common finding and other dental anomalies, such as hypoplastic or hypomineralized enamel, are rare. Fingernails and/or toenails are hypoplastic and have been reported as spoon‐shaped, slow growing and prone to fracture [3, 4]. Nail dysplasia is often worse in childhood, improving with age so that there may be no obvious nail abnormalities as an adult [4].…”

“…Fingernails and/or toenails are hypoplastic and have been reported as spoon‐shaped, slow growing and prone to fracture [3, 4]. Nail dysplasia is often worse in childhood, improving with age so that there may be no obvious nail abnormalities as an adult [4]. Fine, thin, slow‐growing scalp hair [4, 5] and scanty eyebrows or eyelashes [6] have been described in some patients but these are not marked features.…”

“…Nail dysplasia is often worse in childhood, improving with age so that there may be no obvious nail abnormalities as an adult [4]. Fine, thin, slow‐growing scalp hair [4, 5] and scanty eyebrows or eyelashes [6] have been described in some patients but these are not marked features. Heat tolerance and sweating are normal.…”

“…Heat tolerance and sweating are normal. Evidence suggests an autosomal dominant pattern of inheritance [3, 4], although isolated cases without a positive family history have been reported.…”