“…Congenital nasofrontal dermoid cysts (NDC) are uncommon developmental anomalies that comprise up to 61% of midline congenital nasal masses 1. Several cases of familial clustering of NCD have been reported in the literature, documenting this condition across multiple generations, in both sexes, and, in a few cases, in twins 2,3. All these data support the hypothesis of a strong genetic link, which becomes more evident in those syndromic anomalies affecting the embryonic development of head and face.Wardinsky 2 showed 41% of NDC had associated multiple anomalies, especially craniofacial abnormalities (hemifacial microsomia, oral-facial-digital syndrome, frontonasal dysplasia, bitemporal narrowing, single central incisor, broad nasal bridge, coarse facies, ocular hypertelorism, coronal synostosis).…”