Abstract:Abstract. Pregnant normal Wistar rats and Gunn rats were given 25 tzCi (1 mg) 14C-bilirubin intravenously. They were killed at different intervals. Whole-body autoradiography was used to study the different pathways of bilirubin in normal rats and in Gunn rats. Numerous spots of intense blackening were seen on the autoradiographs in the area of the liver of normal rats, indicating biliary excretion of the administered isotope. In the autoradiographic picture of the Gunn rat liver more diffuse blackening was pr… Show more
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