Autonomic testing in patients with chronic fatigue syndrome

Becker, Pascale De; Dendale, Paul; Meirleir, Kenny De; Campine, Isabelle; Vandenborne, Krista; Hagers, Yves

doi:10.1016/s0002-9343(98)00168-5

Cited by 67 publications

(58 citation statements)

References 10 publications

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“…3) showed no significant differences between groups (72 bpm, 95% CI: 67-75 vs 70 bpm, 95% CI: 63-76, respectively). However, the pattern of change over time was significantly different for HR averaged over the mid-tilt; HR increase from baseline was significantly higher in CFS (22 bpm, 95% CI: 17-26) than controls (17 bpm, 95% CI: [13][14][15][16][17][18][19][20]. There was no significant difference for SysP at any time point.…”

Section: Cfs and Orthostatic Intolerancementioning

confidence: 80%

“…Information about HRV in CFS patients (11,12) has commonly been obtained using linear methods such as spectral analysis that analyzes the frequencies of R-R interval waveforms with respect to time. Linear methods yield conflicting results with regard to CFS (13)(14)(15)(16). They rely on stationary and long recordings, not differentiating between increasing and decreasing heart rates, and provide no information on time direction (17).…”

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confidence: 99%

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A Matched Case Control Study of Orthostatic Intolerance in Children/Adolescents With Chronic Fatigue Syndrome

et al. 2008

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This study aimed to define cardiovascular and heart rate variability (HRV) changes following head-up tilt (HUT) in children/adolescents with chronic fatigue syndrome (CFS) in comparison to age-and gender-matched controls. Twenty-six children/ adolescents with CFS (11-19 y) and controls underwent 70-degree HUT for a maximum of 30 min, but returned to horizontal earlier at the participant's request with symptoms of orthostatic intolerance (OI) that included lightheadedness. Using electrocardiography and beat-beat finger blood pressure, a positive tilt was defined as OI with 1) neurally mediated hypotension (NMH); bradycardia (HR Ͻ75% of baseline), and hypotension [systolic pressure (SysP) drops Ͼ25 mm Hg)] or 2) postural orthostatic tachycardia syndrome (POTS); HR increase Ͼ30 bpm, or HR Ͼ120 bpm (with/without hypotension). Thirteen CFS and five controls exhibited OI generating a sensitivity and specificity for HUT of 50.0% and 80.8%, respectively. POTS without hypotension occurred in seven CFS subjects but no controls. POTS with hypotension and NMH occurred in both. Predominant sympathetic components to HRV on HUT were measured in CFS tilt-positive subjects. In conclusion, CFS subjects were more susceptible to OI than controls, the cardiovascular response predominantly manifest as POTS without hypotension, a response unique to CFS suggesting further investigation is warranted with respect to the pathophysiologic mechanisms involved. (Pediatr Res 63: 196-202, 2008)

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Section: Cfs and Orthostatic Intolerancementioning

confidence: 80%

mentioning

confidence: 99%

A Matched Case Control Study of Orthostatic Intolerance in Children/Adolescents With Chronic Fatigue Syndrome

et al. 2008

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“…CFS has sometimes been referred to as the "chronic fatigue immune dysfunction syndrome", because a number of studies have found irregularities of the immune system. Recently, the role of abnormal autonomic function in the pathogenesis of chronic fa-tigue syndrome has been investigated, suggesting potential significance in the diagnostic pro-cess of this condition in the future [24][25][26][27][28][29].…”

Section: Discussionmentioning

confidence: 99%

Chronic fatigue syndrome in 57-year-old woman

et al. 2014

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AbstractChronic fatigue syndrome (CFS) is characterized by unexplained fatigue lasting for more than 6 months and accompanied by flulike symptoms. It most commonly affects women aged between 30 and 60 years. To date, clear diagnostic criteria allowing for unambiguous diagno-sis of CFS have not been established. We present a case of a 57-year-old woman with chronic fatigue syndrome in order to showcase the symptoms of this condition and propose a diagnos-tic protocol.

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“…The process was repeated 3 times with an interval of 1 min. If the Valsalva ratio, the longest RR interval during expiration to the shortest RR interval during expiration, was <1.10, it was considered abnormal [11, 12]. …”

Section: Methodsmentioning

confidence: 99%

Autonomic Nervous Function and Arrhythmias in Patients with Acute Viral Myocarditis during a 6-Month Follow-Up Period

Gao¹,

Peng²,

Qunying³

et al. 2008

Cardiology

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Objective: It was our aim to study the outcome of autonomic nervous function (ANF), heart rate variability (HRV) and arrhythmias in patients with acute viral myocarditis in a 6-month follow-up period after the diagnosis. Methods: ANF was measured in patients with acute viral myocarditis 1, 3 and 6 months after the disease was diagnosed. HRV and arrhythmias were monitored by 24-hour electrocardiogram during the follow-up examination. Results: Ninety-six patients with acute viral myocarditis were enrolled in this study; 58% showed abnormal ANF tests, and the incidence was reduced to 17% after 6 months (p < 0.01). Time and frequency domain analyses of HRV were significantly reduced in the early stage of the disease and recovered after 6 months (p < 0.05). The incidence of arrhythmias in patients with abnormal ANF was significantly higher than in patients with normal ANF (p < 0.05). The incidence of arrhythmias in patients with abnormal ANF at 6 months was significantly lower than that at the first month (p < 0.05). Conclusions: There is a significant impairment of ANF and a higher incidence of arrhythmias in the early stage of acute myocarditis. ANF and HRV abnormalities are significantly improved, and the incidence of arrhythmia is significantly reduced after 6 months in patients with acute myocarditis.

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Autonomic testing in patients with chronic fatigue syndrome

Cited by 67 publications

References 10 publications

A Matched Case Control Study of Orthostatic Intolerance in Children/Adolescents With Chronic Fatigue Syndrome

A Matched Case Control Study of Orthostatic Intolerance in Children/Adolescents With Chronic Fatigue Syndrome

Chronic fatigue syndrome in 57-year-old woman

Autonomic Nervous Function and Arrhythmias in Patients with Acute Viral Myocarditis during a 6-Month Follow-Up Period

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