Autonomic mediation in the interdependences between cardiocortical activity time variations and between cardiorespiratory activity time variations in the lizard, Gallotia galloti

Vera, Luis De; Santana, Alejandro; Pereda, Ernesto; González, José M.

doi:10.1016/j.cbpa.2007.09.012

Cited by 2 publications

(4 citation statements)

References 44 publications

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“…On the other hand, nonlinearity in the HRV of mammals has also been associated with the presence of a respiratory component in the signal that is mainly mediated by the parasympathetic nervous system in rats (19) and humans (15,26,29). In agreement with this argument, the absence of respiratory sinus arrhythmia in G. galloti that we have suggested in previous studies (10,18), would also contribute in parallel to the absence of nonlinearity in lizard RRV in the basal state.…”

Section: Rrv Dynamics From a Nonlinear Technique Point Of Viewsupporting

confidence: 76%

“…This approach quantifies time series by means of tools based mainly on the classical theory of correlation, autoregressive modeling, or the Fourier analysis (11, 35). These tools have proven, and continue to prove, useful in assessing shortterm cardiovascular control in vertebrates (4,5,10,11,17,34). However, as the linearity and homeostaticity of physiological systems began to be challenged during 1990s, new methods, based on system dynamics, have been trying to provide since then an alternative/complementary explanation to the complexity of cardiovascular signals.…”

mentioning

confidence: 99%

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Nonlinearity and fractality in the variability of cardiac period in the lizard,Gallotia galloti: effects of autonomic blockade

Vera¹,

Santana²,

González³

2008

American Journal of Physiology-Regulatory, Integrative and Comp

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Both nonlinear and fractal properties of beat-to-beat R-R interval variability signal (RRV) of freely moving lizards (Gallotia galloti) were studied in baseline and under autonomic nervous system blockade. Nonlinear techniques allowed us to study the complexity, chaotic behavior, nonlinearity, stationarity, and regularity over time of RRV. Scaling behavior of RRV was studied by means of fractal techniques. The autonomic nervous system blockers used were atropine, propranolol, prazosin, and yohimbine. The nature of RRV was linear in baseline and under beta-, alpha(1)- and alpha(2)-adrenoceptor blockades. Atropine changed the linear nature of RRV to nonlinear and increased its stationarity, regularity and fractality. Propranolol increased the complexity and chaotic behavior, and decreased the stationarity, regularity, and fractality of RRV. Both prazosin and yohimbine did not change any of the nonlinear and fractal properties of RRV. It is suggested that 1) the use of both nonlinear and fractal analysis is an appropriate approach for studying cardiac period variability in reptiles; 2) the cholinergic activity, which seems to make the alpha(1)-, alpha(2)- and beta-adrenergic activity interaction unnecessary, determines the linear behavior in basal RRV; 3) fractality, as well as both RRV regularity and stationarity over time, may result from the balance between cholinergic and beta-adrenergic activities opposing actions; 4) beta-adrenergic activity may buffer both the complexity and chaotic behavior of RRV, and 5) neither the alpha(1)- nor the alpha(2)-adrenergic activity seem to be involved in the mediation of either nonlinear or fractal components of RRV.

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Section: Rrv Dynamics From a Nonlinear Technique Point Of Viewsupporting

confidence: 76%

mentioning

confidence: 99%

Nonlinearity and fractality in the variability of cardiac period in the lizard,Gallotia galloti: effects of autonomic blockade

Vera¹,

Santana²,

González³

2008

American Journal of Physiology-Regulatory, Integrative and Comp

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“…This result is quite surprising because the b-adrenoceptor activity is precisely the autonomic activity mainly involved in mediating cardiocortical and cardiorespiratory couplings in lizards (De Vera et al 2008). Further investigation is needed to elucidate this point.…”

Section: Discussionmentioning

confidence: 78%

“…Moreover, a mammalian-style respiratory sinus arrhythmia (RSA), resulting from the interaction between cardiovascular and respiratory systems and based on a dual location for cardiac vagal preganglionic neurons, has been reported in C. d. terrificus (Campbell et al 2006). Conversely, in G. galloti, where there have been no such neuroanatomical studies, spectral (González and De Vera 1988) and nonlinear (De Vera et al 2008) analysis have supported the absence of RSA. This evidence, together with that the respiratory and cardiovascular systems are functionally and neurally related, leads one to propose that the dorsal vagal complex with vagal efferent pathways originating in the dorsal motor nucleus of the vagus is the central structure mainly involved in the phase cardiovascular synchronization in the LF range.…”

Section: Discussionmentioning

confidence: 87%

Autonomic mediation of the interdependence between variability signals of heart rate and blood pressure in the lizard Gallotia galloti

et al. 2012

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Autonomic nervous system (ANS) involvement in the mediation of the synchronization between beat-to-beat RR interval variability (RRIV) and systolic blood pressure variability (SBPV) signals of the lizard Gallotia galloti (Oudart, 1839) was investigated through linear and nonlinear time series analysis methods in a pharmacological blockade context. The ANS blockers used were atropine, prazosin, and propranolol. The interdependence between the signals was quantified by means of the magnitude-squared coherence (MSC), which measures amplitude and phase linear synchronization; the phase lag index (PLI), which evaluates the phase synchronization; and the index L, which quantifies the generalized linear and nonlinear synchronization. Atropine decreased the PLI in the low-frequency (LF: 0.01-0.05 Hz) range; prazosin decreased the MSC in the medium-frequency (MF: 0.06-0.15 Hz) range; and propranolol did not alter any of the interdependence measures. It is suggested that (i) the cholinoceptor activity mediates the phase cardiovascular synchronization in the LF range; (ii) the a1-adrenoceptor activity mediates the amplitude and phase linear cardiovascular synchronization in the MF range; and (iii) the b-adrenoceptor activity plays no role in mediating any dynamics of cardiovascular synchronization in the studied frequency range. When comparing these results with those in mammals, a lesser overall autonomic involvement in the mediation of the studied cardiovascular interdependences is seen in reptiles.Résumé : Des méthodes d'analyse linéaire et non linéaire de séries temporelles ont été utilisées pour étudier le rôle du système nerveux autonome (SNA) dans la médiation de la synchronisation des signaux de variabilité des intervalles RR décalés d'un battement (RRIV) et de la pression sanguine systolique (SBPV) chez le lézard Gallotia galloti Oudart, 1839 dans un contexte de blocage pharmacologique. Les inhibiteurs du SNA utilisés sont l'atropine, la prazonine et le propranolol. L'interdépendance entre les signaux a été quantifiée au module de la fonction de cohérence (MSC), une mesure de la synchronisation linéaire amplitude et phase, de l'indice de déphasage (PLI), une mesure de la synchronisation de phases, et de l'indice L, qui quantifie la synchronisation linéaire et non linéaire généralisée. L'atropine a entraîné une diminution du PLI à basse fréquence (0,01-0,05 Hz) et la prazosine, une diminution du MSC à fréquence intermédiaire (0,06-0,15 Hz), alors que le propranolol n'a eu aucun effet sur les mesures de l'interdépendance. Il est suggéré que (i) l'activité de cholinocepteurs joue un rôle dans la médiation de la synchronisation cardiovasculaire de phases à basse fréquence, (ii) l'activité de l'adrénocep-teur a 1 intervient dans la médiation de la synchronisation cardiovasculaire linéaire de l'amplitude et de la phase à fréquence intermédiaire et (iii) l'activité de l'adrénocepteur b n'intervient dans la médiation d'aucun aspect de la synchronisation cardiovasculaire dans la fourchette de fréquences étudiée. La comparai...

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Autonomic mediation in the interdependences between cardiocortical activity time variations and between cardiorespiratory activity time variations in the lizard, Gallotia galloti

Cited by 2 publications

References 44 publications

Nonlinearity and fractality in the variability of cardiac period in the lizard,Gallotia galloti: effects of autonomic blockade

Nonlinearity and fractality in the variability of cardiac period in the lizard,Gallotia galloti: effects of autonomic blockade

Autonomic mediation of the interdependence between variability signals of heart rate and blood pressure in the lizard Gallotia galloti

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