Autonomic and enteric function profiling can predict disordered gastric emptying in diabetic gastropathy

Hassan, Hamza; Ganguli, Surosree; Rashed, Hani; Johnson, William D.; Bhandari, Bikash; Abell, Thomas L.

doi:10.1007/s11517-020-02300-y

Cited by 5 publications

(5 citation statements)

References 22 publications

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“…58 59 An integrative approach using autonomic and enteric profiling has been applied to diabetic gastropathy to predict gastric emptying. 48 49 50 51 52…”

Section: Autonomic and Enteric Nervous System Measures In Gastropares...mentioning

confidence: 99%

“…Cutaneous EGG has been advocated for some time but has yet to find widespread use or support. 49 The advent of third-generation EGG recordings, such as Body Surface Mapping, may change this as these approaches may result in more distinct phenotypes of GpS patients. Using low-resolution mEGs may provide additional clinically useful information for patients undergoing endoscopy.…”

Section: Full-thickness Biopsies In Gastroparesis Syndromesmentioning

confidence: 99%

“…58,59 An integrative approach using autonomic and enteric profiling has been applied to diabetic gastropathy to predict gastric emptying. [48][49][50][51][52] An additional use of autonomic and/or enteric profiling may be for patients with GpS symptoms and either postural orthostatic tachycardia syndrome and/or Ehlers-Danlos syndrome (EDS). These complex conditions frequently present with the symptoms of gastroparesis as well.…”

Section: Autonomic and Enteric Nervous System Profiling In Gastropare...mentioning

confidence: 99%

“…Gastric-emptying time Patients with combined abnormal values of autonomic and enteric parameters were more likely to be diagnosed with rapid gastric-emptying time than an enteric parameter, EGG alone. 49 A study of patients with diabetic gastroparesis showed that impairment in reflex vasoconstriction (sympathetic hypofunction) was significantly associated with impairment in gastric emptying. 50 In that study, all autonomic function tests were significantly impaired in the diabetes group compared to normal controls.…”

Section: Central and Autonomic Nervous Systems-the Example Of Migrainementioning

confidence: 99%

“…Patients with combined abnormal values of autonomic and enteric parameters were more likely to be diagnosed with rapid gastric-emptying time than an enteric parameter, EGG alone. 49…”

Section: Autonomic and Enteric Nervous System Measures In Gastropares...mentioning

confidence: 99%

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Gastroparesis and Gastroparesis Syndromes as Neuromuscular Disorders

Naing,

Mathur,

Chhabra

et al. 2023

Semin Neurol

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Gastroparesis syndromes (GpS) are a spectrum of disorders presenting with characteristic symptoms increasingly recognized as being gastrointestinal (GI) neuromuscular disorders (NMDs). This review focuses on GpS as a manifestation of neurologic disorders of GI NMD. GpS can be associated with systemic abnormalities, including inflammatory, metabolic, and serologic disorders, as well as autoimmune antibodies via nerve and muscle targets in the GI tract, which can be treated with immunotherapy, such as intravenous immunoglobulin. GpS are associated with autonomic (ANS) and enteric (ENS) dysfunction. Disorders of ANS may interact with the ENS and are the subject of continued investigation. ENS disorders have been recognized for a century but have only recently begun to be fully quantified. Anatomic structural changes in the GI tract are increasingly recognized in GpS. Detailed descriptions of anatomic changes in GpS, and their correlation with physiologic findings, have opened a new era of investigation. The management of GpS, when viewed as GI NMD, has shifted the paradigms of both diagnosis and treatment. This article concludes with current approaches to GpS directed at underlying neuromuscular pathology.

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“…58 59 An integrative approach using autonomic and enteric profiling has been applied to diabetic gastropathy to predict gastric emptying. 48 49 50 51 52…”

Section: Autonomic and Enteric Nervous System Measures In Gastropares...mentioning

confidence: 99%

Section: Full-thickness Biopsies In Gastroparesis Syndromesmentioning

confidence: 99%

Section: Autonomic and Enteric Nervous System Profiling In Gastropare...mentioning

confidence: 99%

Section: Central and Autonomic Nervous Systems-the Example Of Migrainementioning

confidence: 99%

“…Patients with combined abnormal values of autonomic and enteric parameters were more likely to be diagnosed with rapid gastric-emptying time than an enteric parameter, EGG alone. 49…”

Section: Autonomic and Enteric Nervous System Measures In Gastropares...mentioning

confidence: 99%

See 3 more Smart Citations