and diffusivity of the Brownian motion of water molecules. They may be derived from the so-called diffusion tensor [10]. The diffusion tensor can be represented by an ellipsoid, which is characterized by three eigenvalues (λ 1 , λ 2, and λ 3) and three eigenvectors in a local frame of each image voxel. Diffusivity is estimated by the average of the three eigenvalues and anisotropy means that the diffusion has directionality in parts of the brain [11,12]. The fractional anisotropy (FA) gives information about the magnitude portion of the diffusion tensor caused by anisotropy [13,14]. The mean diffusivity (MD) represents the