Automatic Segmentation of Acute Leukemia Cells

Kandil, Ahmed H.; Hassan, Osama A.

doi:10.5120/ijca2016907904

Cited by 2 publications

(1 citation statement)

References 25 publications

(39 reference statements)

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“…Test results show that the proposed model achieves 97.18% accuracy and 97.23% precision. Study 17 proposed an algorithm for the detection of blast cells under specific criteria of image enhancement and processing. It comprises a selection of the panel, use of K-means clustering for segmentation, followed by a refinement process.…”

Section: Related Workmentioning

confidence: 99%

Blood cancer prediction using leukemia microarray gene data and hybrid logistic vector trees model

Rupapara

Rustam

Aljedaani

et al. 2022

Sci Rep

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Blood cancer has been a growing concern during the last decade and requires early diagnosis to start proper treatment. The diagnosis process is costly and time-consuming involving medical experts and several tests. Thus, an automatic diagnosis system for its accurate prediction is of significant importance. Diagnosis of blood cancer using leukemia microarray gene data and machine learning approach has become an important medical research today. Despite research efforts, desired accuracy and efficiency necessitate further enhancements. This study proposes an approach for blood cancer disease prediction using the supervised machine learning approach. For the current study, the leukemia microarray gene dataset containing 22,283 genes, is used. ADASYN resampling and Chi-squared (Chi2) features selection techniques are used to resolve imbalanced and high-dimensional dataset problems. ADASYN generates artificial data to make the dataset balanced for each target class, and Chi2 selects the best features out of 22,283 to train learning models. For classification, a hybrid logistics vector trees classifier (LVTrees) is proposed which utilizes logistic regression, support vector classifier, and extra tree classifier. Besides extensive experiments on the datasets, performance comparison with the state-of-the-art methods has been made for determining the significance of the proposed approach. LVTrees outperform all other models with ADASYN and Chi2 techniques with a significant 100% accuracy. Further, a statistical significance T-test is also performed to show the efficacy of the proposed approach. Results using k-fold cross-validation prove the supremacy of the proposed model.

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Section: Related Workmentioning

confidence: 99%