“…Current literature in OD/OC segmentation make use of classical overlap metrics such as the intersectionover-union (IoU, also known as Jaccard index) (Al-Bander et al, 2018;Edupuganti et al, 2018;Fu et al, 2018;Lim et al, 2015;Sevastopolsky, 2017;Sevastopolsky et al, 2018;Sun et al, 2018;Zilly et al, 2015) and the Dice index (Al-Bander et al, 2018;Edupuganti et al, 2018;Sevastopolsky, 2017;Sevastopolsky et al, 2018;Sun et al, 2018;Zilly et al, 2015). Although different by definition, these two metrics can be computed from each other, as they are defined as ratios of overlap between the predicted area and the manual reference annotation (Taha and Hanbury, 2015).…”