Abstract:Cancer is a group of diseases that involves abnormal cell growth, resulting from genetic perturbations in signaling mechanisms. High resolution RNAseq and microarray assays enable the evaluation of the transcriptional activity of high number of signaling molecules. Furthermore, many signaling pathways are described in publically available databases. Today's challenge lies in the connection of signaling pathways and signaling data to produce predictive models which have the power to validate and identify target… Show more
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