Automatic 3D Intersubject Registration of MR Volumetric Data in Standardized Talairach Space

Collins, D. Louis; Neelin, P.; Peters, T. M.; Evans, Alan C.

doi:10.1097/00004728-199403000-00005

Cited by 3,120 publications

(2,120 citation statements)

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“…Studies were included only if they investigated unmedicated healthy children or adults, used fMRI scanning (unless reported otherwise), and reported the coordinates of activations in the space of the MNI template [Collins et al, 1994] or the atlas of Talairach and Tournoux (1988). When activations were reported in MNI space they were transformed into Talairach and Tournoux coordinates, using a nonlinear transformation (http://imaging.mrc-cbu.cam.ac.…”

Section: Methodsmentioning

confidence: 99%

Social cognition and the brain: A meta‐analysis

Overwalle

2008

Human Brain Mapping

1,479

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This meta-analysis explores the location and function of brain areas involved in social cognition, or the capacity to understand people's behavioral intentions, social beliefs, and personality traits. On the basis of over 200 fMRI studies, it tests alternative theoretical proposals that attempt to explain how several brain areas process information relevant for social cognition. The results suggest that inferring temporary states such as goals, intentions, and desires of other people-even when they are false and unjust from our own perspective-strongly engages the temporo-parietal junction (TPJ). Inferring more enduring dispositions of others and the self, or interpersonal norms and scripts, engages the medial prefrontal cortex (mPFC), although temporal states can also activate the mPFC. Other candidate tasks reflecting general-purpose brain processes that may potentially subserve social cognition are briefly reviewed, such as sequence learning, causality detection, emotion processing, and executive functioning (action monitoring, attention, dual task monitoring, episodic memory retrieval), but none of them overlaps uniquely with the regions activated during social cognition. Hence, it appears that social cognition particularly engages the TPJ and mPFC regions. The available evidence is consistent with the role of a TPJ-related mirror system for inferring temporary goals and intentions at a relatively perceptual level of representation, and the mPFC as a module that integrates social information across time and allows reflection and representation of traits and norms, and presumably also of intentionality, at a more abstract cognitive level.

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Section: Methodsmentioning

confidence: 99%

Social cognition and the brain: A meta‐analysis

Overwalle

2008

Human Brain Mapping

1,479

1,241

View full text Add to dashboard Cite

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“…These volumes were corrected for image intensity nonuniformity , and linearly and nonlinearly transformed into standardized stereotaxic space (Talairach and Tournoux, 1988) using automated feature matching to the MNI305 template (Collins et al, 1994b;Collins and Evans, 1997). Each individual's MRI was then coregistered to their summed radioactivity PET images (Evans et al, 1992).…”

Section: Methodsmentioning

confidence: 99%

Decreasing Amphetamine-Induced Dopamine Release by Acute Phenylalanine/Tyrosine Depletion: A PET/[11C]Raclopride Study in Healthy Men

Leyton

Dagher

Boileau

et al. 2003

Neuropsychopharmacol

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Acute phenylalanine/tyrosine depletion (APTD) has been proposed as a new method to decrease catecholamine neurotransmission safely, rapidly, and transiently. Validation studies in animals are encouraging, but direct evidence in human brain is lacking. In the present study, we tested the hypothesis that APTD would reduce stimulated dopamine (DA) release, as assessed by positron emission tomography (PET) and changes in [ 11 C]raclopride binding potential (BP), a measure of DA D2/D3 receptor availability. Eight healthy men received two PET scans, both following d-amphetamine, 0.3 mg/kg, p.o., an oral dose known to decrease [ 11 C]raclopride BP in ventral striatum. On the morning before each scan, subjects ingested, in counter-balanced order, an amino-acid mixture deficient in the catecholamine precursors, phenylalanine, and tyrosine, or a nutritionally balanced mixture. Brain parametric images were generated by calculating [ 11 C]raclopride BP at each voxel. BP values were extracted from the t-map (threshold: t ¼ 4.2, equivalent to po0.05, Bonferroni corrected) and a priori identified regions of interest from each individual's coregistered magnetic resonance images. Both receptor parametric mapping and region of interest analyses indicated that [ 11 C]raclopride binding was significantly different on the two test days in the ventral striatum (peak t ¼ 6.31; x ¼ À25, y ¼ À8, and z ¼ 0.1). In the t-map defined cluster, [ 11 C]raclopride BP values were 11.8 7 11.9% higher during the APTD session (po0.05). The reduction in d-amphetamine-induced DA release exhibited a linear association with the reduction in plasma tyrosine levels (r ¼ À0.82, po0.05). Together, the results provide the first direct evidence that APTD decreases stimulated DA release in human brain. APTD may be a suitable new tool for human neuropsychopharmacology research.

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“…The first step is to transform the native MRIs into a standardized stereotaxic coordinate space based on the Talairach atlas (Talairach and Tournoux, 1988). This procedure uses an automatic, multi-scale feature-matching algorithm (Collins et al, 1994) that performs a 9-parameter linear transformation to match each brain to a template brain. The images were corrected for nonuniformity artifacts (Sled et al, 1998).…”

Section: Automated Lesion Detectionmentioning

confidence: 99%

Focal cortical atrophy in multiple sclerosis: Relation to lesion load and disability

Charil¹,

Dagher²,

Lerch³

et al. 2007

NeuroImage

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Multiple sclerosis (MS) is thought to predominantly affect white matter (WM). Recently, however, loss of cortical gray matter has also been described. Little is known about the cause of cortical atrophy in MS, whether it occurs early in the disease course, and whether it affects all cortical regions equally or if there is a preferential pattern of focal cortical atrophy. An automated method was used to compute the thickness at every vertex of the cortical surface of the brains of 425 early relapsing-remitting MS patients. We correlated cortical thickness with the WM lesion load and the Expanded Disability Status Scale score. Mean cortical thickness correlated with WM lesion load and disability. The correlations of cortical thickness with total lesion load and disability were most significant in cingulate gyrus, insula, and associative cortical regions. Conversely, primary sensory, visual, and motor areas showed a less significant relationship. The highest amount of atrophy per lesion volume or disability scale unit was in the anterior cingulate cortex. This study confirms the relation between cortical atrophy, WM lesion load, and disability in MS, and suggests that cortical atrophy occurs even in MS patients with only mild disability. Most interestingly, we show a specific regional pattern of focal atrophy in MS that is distinctively different from the one in normal aging. The predilection of the atrophic process for areas that are heavily interconnected with other brain regions suggests that interruption of WM tracts by MS plaques contributes, at least in part, to the development of cortical atrophy.

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Automatic 3D Intersubject Registration of MR Volumetric Data in Standardized Talairach Space

Cited by 3,120 publications

References 0 publications

Social cognition and the brain: A meta‐analysis

Social cognition and the brain: A meta‐analysis

Decreasing Amphetamine-Induced Dopamine Release by Acute Phenylalanine/Tyrosine Depletion: A PET/[11C]Raclopride Study in Healthy Men

Focal cortical atrophy in multiple sclerosis: Relation to lesion load and disability

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