“…In recent years, the presence of such genes is being consistently detected in different Aquimarina strains via genome sequencing (Keller-Costa et al, 2016;Ranson et al, 2018;Hudson et al, 2019). Moreover, structure elucidation of cuniculene, the first trans-AT polyketide ever reported from Aquimarina, has just been achieved (Helfrich et al, 2019). In this context, this study benefits from recent advances in computational biology and in silico genome mining (Medema et al, 2015;Blin et al, 2017;Medema, 2018;Navarro-muñoz et al, 2018) to examine the abundance, diversity, phylogenetic relationships and co-occurrence networks of secondary metabolite biosynthetic gene clusters (BGCs) across all publicly available Aquimarina genomes as of February 25, 2019, substantially enlarging the known genetic space underlying natural product biosynthesis within the Bacteroidetes phylum.…”