Automated low flow pump system for the treatment of refractory ascites: A multi-center safety and efficacy study

Alfapump® system vs. large volume paracentesis for refractory ascites: A multicenter randomized controlled study

“…The alfapump was surgically inserted subcutaneously in the upper right quadrant of the abdomen, as described [12]. Perioperative antibiotics (ceftazidime 2 g and teicoplanin 400 mg pre-surgery and again 12 h post surgery) were recommended; deviations were allowed according to local practice.…”

“…Over 6 months, 71% of AP patients are expected to require LVP [12]. Conservatively estimating 97% of SoC patients require LVP over 6 months equates to a hazard ratio (SoC:AP) of 2.83 [18].…”

“…PIONEER, a prospective, open label, uncontrolled study, demonstrated the safety of the alfapump system and a significant reduction in the need for paracentesis in patients with RA. The study, however, lacked a control group [12].…”

Patient Selection, Outcome and Clinical Efficacy of TIPS: A Single Center Experience and Review of the Literature

“…In children, peritoneovenous shunting have been used for the treatment of intractable malignant ascites, but the patency of this shunt system is limited [43] and no data with cirrhotic patients were found. The role of a recently available surgically implanted automated flow pump system from the peritoneal cavity into the bladder [44] has to be further…”

Palliative long-term abdominal drains in refractory ascites due to end-stage liver disease: A case series

“…Individuals with RA often have contraindications for other interventions such as transjugular intrahepatic portosystemic shunts (TIPSS) and the ALFA pump (7,8,9).…”