Automated headspace solid-phase microextraction and on-fiber derivatization for the determination of clenbuterol in meat products by gas chromatography coupled to mass spectrometry

Jiang, Yong; Ni, Yongnian

doi:10.1002/jssc.201400634

Cited by 19 publications

(12 citation statements)

References 38 publications

(41 reference statements)

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“…Gas chromatography–mass spectrometry (GC‐MS) coupled with solid‐phase microextraction (SPME) has been successfully employed for the qualitative and quantative analysis of volatile and semivolatile compounds in many fields, such as the determination of fruits (Jiang, Ni, Zhu, & Zhu, ; Nardini et al, ; Perestrelo, Barros, Rocha, & Câmara, ), fruit juice (Balme & Gülaçar, ), vegetables (Murat, Gourrat, Jerosch, & Cayot, ), meat (Jiang & Ni, ), wines (Burin, Marchand, De Revel, & Bordignon‐Luiz, ), and plants (Chai et al, ). SPME was introduced first by Arthur and Pawlizyn (Arthur & Pawliszyn, ) in 1990, which integrates sampling, extraction, concentration, and sample introduction to GC.…”

Section: Introductionmentioning

confidence: 99%

Identification and changes of different volatile compounds in meat of crucian carp under short-term starvation by GC-MS coupled with HS-SPME

Jiang

Yüan

et al. 2017

Journal of Food Biochemistry

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The different volatile compounds in meat of crucian carp under short‐term starvation stress were investigated in this study by headspace solid‐phase microextraction combined with gas chromatography‐mass spectrometric analysis. The detail workflow included Mzmine, analysis of variance, automatic mass spectral deconvolution and identification system (AMDIS), and genetic algorithm. Seventy‐two kinds of volatile compounds were identified by AMDIS and 42 kinds of different compounds were selected including 19 aromatics, 7 alcohols, 1 ketones, 2 aldehydes, 2 esters, and 11 unknown compounds. Samples from starvation groups were separated clearly on principal components analysis by 42 volatile compounds. The results suggest that starvation could cause the change of flavor of fish meat, and the changing patterns of these different volatile compounds were revealed. Practical applications In southern China, farm‐raised crucian carps are usually put into clean water under short‐term starvation for eliminating smell before they are sold. This phenomenon has attracted the attention of the researcher. The present study reveals the changing patterns of volatile compounds in meat of crucian carp by using headspace solid‐phase microextraction–gas chromatography/mass spectrometry and starvation groups were classified based on the volatile data. The results demonstrated that combination of Mzmine, ANOVA, AMDIS, and GA can be applied to select different volatile compounds successfully, and this method could be used for the identification of different compounds in similar gas chromatography–mass spectrometry analysis.

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Section: Introductionmentioning

confidence: 99%

Identification and changes of different volatile compounds in meat of crucian carp under short-term starvation by GC-MS coupled with HS-SPME

Jiang

Yüan

et al. 2017

Journal of Food Biochemistry

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“…As a simple, sensitive, and solvent-free technique, HS-SPME has been widely applied to determine the volatile compositions of medicines [34,35], drink [36][37][38], food [39,40], and fruits [41][42][43].…”

Section: Introductionmentioning

confidence: 99%

“…Headspace solid‐phase microextraction (HS‐SPME) is a sampling and concentration technique for analysis of volatile and semi‐volatile substances in a large variety of matrices. As a simple, sensitive, and solvent‐free technique, HS‐SPME has been widely applied to determine the volatile compositions of medicines , drink , food , and fruits .…”

Section: Introductionmentioning

confidence: 99%

Rapid determination of the volatile components in tobacco by ultrasound‐microwave synergistic extraction coupled to headspace solid‐phase microextraction with gas chromatography‐mass spectrometry

Yang

Chu

Guang-hong

et al. 2016

J of Separation Science

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An ultrasound-microwave synergistic extraction coupled to headspace solid-phase microextraction was first employed to determine the volatile components in tobacco samples. The method combined the advantages of ultrasound, microwave, and headspace solid-phase microextraction. The extraction, separation, and enrichment were performed in a single step, which could greatly simplify the operation and reduce the whole pretreatment time. In the developed method, several experimental parameters, such as fiber type, ultrasound power, and irradiation time, were optimized to improve sampling efficiency. Under the optimal conditions, there were 37, 36, 34, and 36 components identified in tobacco from Guizhou, Hunan, Yunnan, and Zimbabwe, respectively, including esters, heterocycles, alkanes, ketones, terpenoids, acids, phenols, and alcohols. The compound types were roughly the same while the contents were varied from different origins due to the disparity of their growing conditions, such as soil, water, and climate. In addition, the ultrasound-microwave synergistic extraction coupled to headspace solid-phase microextraction method was compared with the microwave-assisted extraction coupled to headspace solid-phase microextraction and headspace solid-phase microextraction methods. More types of volatile components were obtained by using the ultrasound-microwave synergistic extraction coupled to headspace solid-phase microextraction method, moreover, the contents were high. The results indicated that the ultrasound-microwave synergistic extraction coupled to headspace solid-phase microextraction technique was a simple, time-saving and highly efficient approach, which was especially suitable for analysis of the volatile components in tobacco.

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“…β 2 ‐Agonists, such as salbutamol (SAL) and clenbuterol (CLE), are a class of veterinary drugs used in food‐producing animals to promote leanness of meat . The illegal abuse of β 2 ‐agonists in breeding is detrimental to both animal and human health by inducing heart palpitations, diarrhea, muscle tremors, and even malignant tumors .…”

Section: Introductionmentioning

confidence: 99%

Novel method for the rapid and specific extraction of multiple β₂‐agonist residues in food by tailor‐made Monolith‐MIPs extraction disks and detection by gas chromatography with mass spectrometry

Gan

Chen

et al. 2016

J of Separation Science

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A quick and specific pretreatment method based on a series of extraction clean-up disks, consisting of molecularly imprinted polymer monoliths and C18 adsorbent, was developed for the specific enrichment of salbutamol and clenbuterol residues in food. The molecularly imprinted monolithic polymer disk was synthesized using salbutamol as a template through a one-step synthesis process. It can simultaneously and specifically recognize salbutamol and clenbuterol. The monolithic polymer disk and series of C18 disks were assembled with a syringe to form a set of tailor-made devices for the extraction of target molecules. In a single run, salbutamol and clenbuterol can be specifically extracted, cleaned, and eluted by methanol/acetic acid/H2 O. The target molecules, after a silylation derivatization reaction were detected by gas chromatography-mass spectrometry. The parameters including solvent desorption, sample pH, and the cycles of reloading were investigated and discussed. Under the optimized extraction and clean-up conditions, the limits of detection and quantitation were determined as 0.018-0.022 and 0.042-0.049 ng/g for salbutamol and clenbuterol, respectively. The assay described was convenient, rapid, and specific; thereby potentially efficient in the high-throughput analysis of β2 -agonists residues in real food samples.

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Automated headspace solid-phase microextraction and on-fiber derivatization for the determination of clenbuterol in meat products by gas chromatography coupled to mass spectrometry

Cited by 19 publications

References 38 publications

Identification and changes of different volatile compounds in meat of crucian carp under short-term starvation by GC-MS coupled with HS-SPME

Identification and changes of different volatile compounds in meat of crucian carp under short-term starvation by GC-MS coupled with HS-SPME

Rapid determination of the volatile components in tobacco by ultrasound‐microwave synergistic extraction coupled to headspace solid‐phase microextraction with gas chromatography‐mass spectrometry

Novel method for the rapid and specific extraction of multiple β₂‐agonist residues in food by tailor‐made Monolith‐MIPs extraction disks and detection by gas chromatography with mass spectrometry

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Automated headspace solid-phase microextraction and on-fiber derivatization for the determination of clenbuterol in meat products by gas chromatography coupled to mass spectrometry

Cited by 19 publications

References 38 publications

Identification and changes of different volatile compounds in meat of crucian carp under short-term starvation by GC-MS coupled with HS-SPME

Identification and changes of different volatile compounds in meat of crucian carp under short-term starvation by GC-MS coupled with HS-SPME

Rapid determination of the volatile components in tobacco by ultrasound‐microwave synergistic extraction coupled to headspace solid‐phase microextraction with gas chromatography‐mass spectrometry

Novel method for the rapid and specific extraction of multiple β2‐agonist residues in food by tailor‐made Monolith‐MIPs extraction disks and detection by gas chromatography with mass spectrometry

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Product

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Novel method for the rapid and specific extraction of multiple β₂‐agonist residues in food by tailor‐made Monolith‐MIPs extraction disks and detection by gas chromatography with mass spectrometry