Automated detection of malaria with haematology analyzer sysmex xe-2100

Abstract

Flowcytometric analyzer is a rapid, high throughput device which needs less expertization for the diagnosis of malaria. Hence, it can be used in the diagnostic laboratories as an early modality for diagnosis of malaria in suspected as well as clinically in apparent cases.

Hematology analyzers to identify malaria and dengue

“…[1] This is the first report on using automated hematology analyzer for help diagnose and differentiate malaria and dengue from other infections. [2][3][4] The common parameters that seem to be specific for malaria include lymphocyte and platelet parameters. The feasibility of using hematology analyzer is very interesting.…”

“…[1] In fact, the use of automated hematology analyzer for determination of malaria and dengue has been in trials for a long time. [2][3][4] The fair diagnostic properties (sensitivity and specificity) of the automated hematology diagnosis can be observed. If this approach is effective, it might help diagnose the diseases for the practitioners who have no experience with two tropical infections.…”

“…The feasibility of using hematology analyzer is very interesting. [2][3][4] Mohapatra et al proposed that the use of hematology analyzer resulted in "a rapid, high throughput device which needs less expertization for the diagnosis of malaria." Focusing on malaria, there are previous reports on using Cell-Dyn ® , Coulter ® GEN·S as well as LH750 automated hematology analyzers.…”

“…If this approach is effective, it might help diagnose the diseases for the practitioners who have no experience with two tropical infections. [3] Focusing on dengue, automated hematology analyzer can be applied in diagnosis. [2][3][4] The common parameters that seem to be specific for malaria include lymphocyte and platelet parameters.…”

“…[2,3] Analysis of the confirm cases records showed that ages ranged from 7 to 50 years with only 21% (7/33) in the 0-14 years range [ Table 1]. A total of 33 sera (89.2%) had elevated levels of HEV IgM consistent with recent infection, only one (2.7%) had elevated levels of HEV IgG without HEV IgM indicating a past infection, and three (8.1%) were negative for HEV antibodies.…”