Automated Characterization of Cyclic Alternating Pattern Using Wavelet-Based Features and Ensemble Learning Techniques with EEG Signals

The Cyclic Alternating Pattern (CAP) is a periodic activity detected in the electroencephalogram (EEG) signals. This pattern was identified as a marker of unstable sleep with several possible clinical applications; however, there is a need to develop automatic methodologies to facilitate real-world applications based on CAP assessment. Therefore, a deep learning-based EEG channels’ feature level fusion was proposed in this work and employed for the CAP A phase classification. Two optimization algorithms optimized the channel selection, fusion, and classification procedures. The developed methodologies were evaluated by fusing the information from multiple EEG channels for patients with nocturnal frontal lobe epilepsy and patients without neurological disorders. Results showed that both optimization algorithms selected a comparable structure with similar feature level fusion, consisting of three electroencephalogram channels (Fp2–F4, C4–A1, F4–C4), which is in line with the CAP protocol to ensure multiple channels’ arousals for CAP detection. Moreover, the two optimized models reached an area under the receiver operating characteristic curve of 0.82, with average accuracy ranging from 77% to 79%, a result in the upper range of the specialist agreement and best state-of-the-art works, despite a challenging dataset. The proposed methodology also has the advantage of providing a fully automatic analysis without requiring any manual procedure. Ultimately, the models were revealed to be noise-resistant and resilient to multiple channel loss, being thus suitable for real-world application.

Section: Discussionmentioning

confidence: 99%

Multiple Time Series Fusion Based on LSTM: An Application to CAP A Phase Classification Using EEG

Mendonça

Mostafa

Freitas

et al. 2022

“…The Z-score normalization is calculated using MATLAB 2016 [ 3 , 36 , 37 ] for the BCG signals. The Z-score value for each BCG signals was calculated using Equation ( 1 ) as described in [ 36 , 38 , 39 ].

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Section: Methodsmentioning

confidence: 99%

Automated Detection of Hypertension Using Continuous Wavelet Transform and a Deep Neural Network with Ballistocardiography Signals

Rajput

Sharma

Kumar

et al. 2022

Self Cite

Managing hypertension (HPT) remains a significant challenge for humanity. Despite advancements in blood pressure (BP)-measuring systems and the accessibility of effective and safe anti-hypertensive medicines, HPT is a major public health concern. Headaches, dizziness and fainting are common symptoms of HPT. In HPT patients, normalcy may be observed at one instant and abnormality may prevail during a long duration of 24 h ambulatory BP. This may cause difficulty in identifying patients with HPT, and hence there is a possibility that individuals may be untreated or administered insufficiently. Most importantly, uncontrolled HPT can lead to severe complications (stroke, heart attack, kidney disease, and heart failure), mainly ignoring the signs in nascent stages. HPT in the beginning stages may not present distinct symptoms and may be difficult to diagnose from standard physiological signals. Hence, ballistocardiography (BCG) signal was used in this study to detect HPT automatically. The processed signals from BCG were converted into scalogram images using a continuous wavelet transform (CWT) and were then fed into a 2-D convolutional neural network model (2D-CNN). The model was trained to learn and recognize BCG patterns of healthy controls (HC) and HPT classes. Our proposed model obtained a high classification accuracy of 86.14% with a ten-fold cross-validation (CV) strategy. Hence, this is the first use of a 2D-CNN model (deep-learning algorithm) to detect HPT employing BCG signals.

“…Sleep stages S3 and S4 are combined into a stage called N3, as per the American Academy of Sleep Medicine’s (AASM) [ 2 ] guidelines. Thus, according to the AASM, the NREM stage consists of only three sleep stages, namely N1, N2, and N3 [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

An Automated Wavelet-Based Sleep Scoring Model Using EEG, EMG, and EOG Signals with More Than 8000 Subjects

Sharma

Yadav

Tiwari

et al. 2022

Self Cite

Human life necessitates high-quality sleep. However, humans suffer from a lower quality of life because of sleep disorders. The identification of sleep stages is necessary to predict the quality of sleep. Manual sleep-stage scoring is frequently conducted through sleep experts’ visually evaluations of a patient’s neurophysiological data, gathered in sleep laboratories. Manually scoring sleep is a tough, time-intensive, tiresome, and highly subjective activity. Hence, the need of creating automatic sleep-stage classification has risen due to the limitations imposed by manual sleep-stage scoring methods. In this study, a novel machine learning model is developed using dual-channel unipolar electroencephalogram (EEG), chin electromyogram (EMG), and dual-channel electrooculgram (EOG) signals. Using an optimum orthogonal filter bank, sub-bands are obtained by decomposing 30 s epochs of signals. Tsallis entropies are then calculated from the coefficients of these sub-bands. Then, these features are fed an ensemble bagged tree (EBT) classifier for automated sleep classification. We developed our automated sleep classification model using the Sleep Heart Health Study (SHHS) database, which contains two parts, SHHS-1 and SHHS-2, containing more than 8455 subjects with more than 75,000 h of recordings. The proposed model separated three classes if sleep: rapid eye movement (REM), non-REM, and wake, with a classification accuracy of 90.70% and 91.80% using the SHHS-1 and SHHS-2 datasets, respectively. For the five-class problem, the model produces a classification accuracy of 84.3% and 86.3%, corresponding to the SHHS-1 and SHHS-2 databases, respectively, to classify wake, N1, N2, N3, and REM sleep stages. The model acquired Cohen’s kappa (κ) coefficients as 0.838 with SHHS-1 and 0.86 with SHHS-2 for the three-class classification problem. Similarly, the model achieved Cohen’s κ of 0.7746 for SHHS-1 and 0.8007 for SHHS-2 in five-class classification tasks. The model proposed in this study has achieved better performance than the best existing methods. Moreover, the model that has been proposed has been developed to classify sleep stages for both good sleepers as well as patients suffering from sleep disorders. Thus, the proposed wavelet Tsallis entropy-based model is robust and accurate and may help clinicians to comprehend and interpret sleep stages efficiently.